netFormulary
 Report : A-Z of formulary items 18/10/2018 05:04:38
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Section Name Details
08.01.02 Daunorubicin  Treatment of leukaemia and AIDs related Kaposi's sarcoma (liposomal formulation only)
05.03.01 Abacavir  HIV infection in combination with other antiretroviral drugs
05.03.01 Abacavir/lamivudine  HIV infection in combination with other antiretroviral drugs
05.03.01 Abacavir/lamivudine/zidovudine  HIV infection in combination with other antiretroviral drugs
(For patients stabilised on the individual components in the same proportions)
10.01.03 Abatacept Orencia®

Treatment of moderate to severe active rheumatoid arthritis, juvenile idiopathic arthritis (adults)

02.09 Abciximab  Prevention of ischaemic cardiac complications in patients undergoing percutaneous coronary intervention. Short-term prevention of myocardial infarction in patients with unstable angina not responding to conventional treatment and who are scheduled for percutaneous coronary intervention
08.03.04.02 Abiraterone  Treatment of metastatic castration resistant prostate cancer in asymptomatic or mildly symptomatic men after failure of androgen deprivation therapy in whom chemotherapy is not yet clinically indicated, or when disease has progressed on or after a docetaxel-based chemotherapy regimen
04.10.01 Acamprosate Campral EC® maintenance of abstinence in alcohol depenence
11.06 Acetazolamide 250 mg tablets & MR capsules  To reduce intraocular pressure in glaucoma. To reduce abnormal retention of fluids. Adjunct in the treatment of epilepsy
11.06 Acetazolamide injection  Reduction of intraocular pressure in glaucoma. In conjunction with: other diuretics in the treatment of fluid retaining states; other anticonvulsants in the treatment of epilepsy
12.01.01 Acetic acid spray  Treatment of otitis externa
11.08.02 Acetylcholine Chloride Miochol-E® To obtain rapid complete miosis in cataract surgery, penetrating keratoplasty, iridectomy, and anterior segment surgery
11.08.01 Acetylcysteine 10% eye drops  Unlicensed preparation
11.08.01 Acetylcysteine 5% eye drops  
11.03.03 Aciclovir 3% eye ointment   Treatment of viral eye infections
05.03.02.01 Aciclovir injection  Treatment of Herpes simplex, Herpes zoster and Varicella zoster infections
05.03.02.01 Aciclovir oral  Treatment of shingles (zoster) and chicken pox
13.05.02 Acitretin Neotigason® Severe extensive psoriasis; palmoplantor pustular psoriasis; severe congenital icthyosis; severe keratosis follicularis
03.01.02 Aclidinium Eklira Genuair®
03.01.04 Aclidinium & formoterol inhaler Duaklir Genuair ®
01.05.03 Adalimumab 

Treatment of Crohn’s disease and ulcerative colitis 

10.01.03 Adalimumab 

Treatment of active rheumatoid arthritis,active progressive psoriatic arthritis and juvenile idiopathic arthritis (Adults)

13.05.03 Adalimumab  Severe active ankylosing spondylitis, severe chronic plaque psoriasis

02.03.02 Adenosine  Rapid conversion to a normal sinus rhythm of paroxysmal supraventricular tachycardias. Aid to diagnosis of broad or narrow complex supraventricular tachycardias
08.01.05 Afatinib  Treatment of Epidermal Growth Factor Receptor TKI-naïve adult patients with locally advanced or metastatic non-small cell lung cancer with activating eGFR mutation(s)
08.01.05 Aflibercept  Treatment of metastatic colorectal cancer
Not recommended by NICE
11.08.02 Aflibercept 

Treatment of neovascular (wet) age-related macular degeneration, visual impairment due to macular oedema secondary to retinal vein occlusion, visual impairment due to diabetic macular oedema

09.08.01 Agalsidase Alfa   Long-term enzyme replacement therapy in Fabry's Disease (α-galactosidase A deficiency)
09.08.01 Agalsidase Beta  Long-term enzyme replacement therapy in patients with Fabry's Disease (α-galactosidase A deficiency)
05.05.01 Albendazole  Treatment of cysts caused by Echinococcus granulosus and alveolar echinococcosis due to E. multilocularis, hookworms, cutaneous larva migrans and Srongyloides stercoralis
06.01.02.03 Albiglutide  Treatment of Type 2 diabetes mellitus
02.11 Albutrepenonacog alfa  Treatment and prophylaxis of bleeding in patients with haemophilia B
08.02.04 Aldesleukin Proleukin® Treatment of renal cell carcinoma
08.01.05 Alectinib  Treatment of lung cancer
08.02.03 Alemtuzumab  Treatment of relapsing remitting multiple sclerosis with active disease
06.06.02 Alendronic Acid tablets 
15.01.04.03 Alfentanil  Analgesia and suppression of respiratory activity in mechanically ventilated patients
09.08.01 Alglucosidase Alfa  Long term enzyme replacement therapy in Pompe disease
02.12 Alirocumab 

Treatment of primary hypercholesterolemia and mixed dyslipidaemia

02.05.05.03 Aliskiren  Use as fourth or fifth line option
13.05.01 Alitretinoin 

Treatment of severe chronic hand eczema

10.01.04 Allopurinol 
06.01.02.03 Alogliptin tablets 
07.04.05 Alprostadil injecton  Treatment of Erectile Dysfunction
02.10.02 Alteplase  Thrombolytic treatment in acute myocardial infarction or acute massive pulmonary embolism or occluded central venous access devices, fibrinolytic treatment of acute ischaemic stroke
04.09.01 Amantadine 

Treatment of Parkinson's disease

SecondLine- 

05.03.04 Amantadine   Prophylaxis and treatment of influenza Not recommended by NICE
02.05.01 Ambrisentan  Treatment of pulmonary arterial hypertension
05.01.04 Amikacin  Treatment of serious infections due to Gram-negative bacteria or staphylococcal disease.
02.03.02 Amiodarone  Treatment of cardiac arrhythmias
04.02.01 Amisulpride 

Treatment of acute and chronic psychoses

 SecondLine-

 

04.07.03 Amitriptyline 
04.07.03 Amitriptyline liquid  Unlicensed indication
Swallowing difficulties, prescribe licensed strengths
04.03.01 Amitriptyline tablets 
02.06.02 Amlodipine 
05.01.01.03 Amoxicillin oral  Treatment of infective exacerbation of COPD and community acquired pneumonia, and sinusitis and acute otitis media only where antibiotics necessary. For tooth abscess only when dentist unavailable. Part of Helicobacter pylori eradication
05.02 Amphotericin  Treatment of systemic fungal infections when toxicity precludes the use of conventional amphotericin
05.02 Amphotericin AmBisome® Treatment of mycoses where toxicity precludes the use of conventional amphoteracin, aspergillosis and visceral leishmaniasis
11.03.02 Amphotericin eye drops  Treatment of ophthalmic fungal infections
05.02 Amphotericin infusion Fungizone® Treatment of systemic fungal infections
09.01.04 Anagrelide 
08.03.04.01 Anastrozole  Treatment breast cancer
05.02.04 Anidulafungin  Treatment of invasive candidiasis
14.05.03 Anti-D (Rh0) Immunoglobulin 

Prophylaxis for women who are rhesus D negative

02.08.02 Apixaban  Prophylaxis of venous thromboembolism following knee or hip surgery -
full course to be given post operation by provider

02.08.02 Apixaban 

Treatment and prevention of thromboembolic events, and stroke prevention in atrial fibrillation

Specialist to complete SIDC

04.09.01 Apomorphine  Third-line option - Treatment of Parkinson's disease
11.08.02 Apraclonidine Iopidine® 0.5% for control of intra-ocular pressure

1% for peri-operative use only
13.05.03 Apremilast 

Treatment of plaque psoriasis and psoriatic arthritis

04.06 Aprepitant  Treatment of nausea & vomiting associated with moderately and highly emetogenic chemotherapy
06.02.02 Aqueous Iodine 

Pre-operative treatment of thyrotoxicosis

SecondLine-

02.08.01 Argatroban  Anticoagulation in patients with heparin-induced thrombocytopenia type II who require parenteral antithrombotic therapy
09.08.01 Arginine   Acute/maintenance treatment of hyperammonaemia in:
carbamylphosphate synthetase deficiency, ornithine carbamyl transferase deficiency, citrullinaemia, arginosuccinic aciduria
09.08.01 Arginine   Treatment of urea cycle disorders
04.02.02 Aripiprazole long acting injection 

Treatment of schizophrenia, specialist to complete SIDC

SecondLine-

04.02.01 Aripiprazole tablets 

Treatment of schizophrenia and episodes of mania 

 Preferred-

08.01.05 Arsenic Trioxide  For induction of remission and consolidation of relapsed refractory acute promyelocytic leukaemia
15.02 Articaine Hydrochloride with Adrenaline 

Infiltration anaesthesia in dentistry

09.08.01 Asfotase alfa  Long-term enzyme replacement therapy in patients with paediatric-onset hypophosphatasia
08.01.05 Asparaginase  Treatment of acute lymphoblastic leukaemia
02.09 Aspirin 75 mg dispersible tablets 
05.03.01 Atazanavir  Treatment of HIV infection
05.03.01 Atazanavir sulfate & cobicistat  Treatment of HIV infection
02.04 Atenolol tablets 
08.01.05 Atezolizumab 

Locally or advanced urothelia cancer when cisplatin unsuitable

04.04 Atomoxetine Strattera®

Treatment of Attention Deficit Hyperactivity Disorder

SecondLine-

02.12 Atorvastatin tablet 
07.01.03 Atosiban  To delay imminent pre-term labour

05.04.08 Atovaquone  Acute treatment of mild to moderate Pneumocystis pneumonia in patients who are intolerant of co-trimoxazole therapy
15.01.05 Atracurium   Adjunct to general anaesthesia during surgical and other procedures and to facilitate endotracheal intubation and mechanical ventilation
08.03.04.02 Atrasentan  Treatment of prostate cancer
11.05 Atropine 1% eye drops  
08.02.03 Avelumab Bavencio®

Treatment of metastatic (secondary) Merkel cell carcinoma in adults

07.04.05 Aviptadil/phentolamine injection Invicorp® Treatment of erectile dysfuction
08.01.05 Axitinib  Treatment of advanced renal cell carcinoma
08.01.03 Azacitidine 

Treatment of myelodysplastic syndromes, chronic myelomonocytic leukaemia and acute myeloid leukaemia in adults

01.05 Azathioprine  Treatment of inflammatory bowel disease
08.02.01 Azathioprine 

Suppression of renal transplant rejection and treatment of vasculitis

08.02.01 Azathioprine  Treatment of autoimmune cytopenias and dermatomyositis
10.01.03 Azathioprine 

Treatment of rheumatoid arthritis

11.03.01 Azithromycin dehydrate 1.5% eye drops 
05.01.05 Azithromycin oral  Treatment of Chlamydia trachomatis
05.01.02.03 Aztreonam injection  Treatment of gram-negative infections
05.01.02.03 Aztreonam nebuliser solution  Suppressive therapy of chronic pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis - all new patients
05.01.02.03 Aztreonam nebuliser solution  Suppressive therapy of chronic pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis. Existing patients until repatriated to secondary care
10.02.02 Baclofen  Treatment of chronic severe spasticity
01.05.01 Balsalazide   Treatment of mild-to-moderate active ulcerative colitis and maintenance of remission
10.01.03 Baricitinib 

Treatment of rheumatoid arthritis

08.02.02 Basiliximab 

Prophylaxis of acute rejection in allogenic renal transplant

08.02.04 BCG bladder instillation  Treatment of carcinoma-in-situ of the urinary bladder and prevention of recurrence of superficial papillary transitional cell carcinoma of the urinary bladder after transurethral resection
03.02 Beclometasone Easyhaler®
03.02 Beclometasone Clenil Modulite®
03.02 Beclometasone Qvar®
01.05.02 Beclometasone oral  Treatment of mild or moderate ulcerative colitis in active phase
03.02 Beclometasone with formoterol 100/6 Fostair® MDI, Fostair® NEXThaler
03.02 Beclometasone with formoterol 200/6 Fostair® MDI, Fostair® NEXThaler
03.02 Beclometasone/formoterol/glycopyrronium Trimbow®
03.04.02 Bee Allergen Extracts  Diagnosis and treatment of IgE-mediated allergy to bee venom
10.01 Belimumab  Add-on therapy for systemic lupus erythematosus
08.01.01 Bendamustine  Treatment of chronic lymphocytic leukaemia, non-Hodgkin's lymphoma and multiple myeloma
02.02.01 Bendroflumethiazide tablets 
05.01.01.01 Benzylpenicillin  Treatment of bacterial meningitis
09.08.01 Betaine  Adjunctive treatment of homocystinuria
11.04.01 Betamethasone 0.1% eye drops  Maximum 10 days treatment
11.04.01 Betamethasone 0.1% eye ointment  Maximum 10 days treatment
08.01.05 Bevacizumab  Treatment of breast, renal cell, lung, colorectal, ovarian, fallopian tube, or peritoneal cancer
11.08.02 Bevacizumab intravitreal injection  Treatment option for AMD,non-AMD eye conditions
Outside of NICE TA -choroidal neovascularisation (CNV) disorders
08.01.05 Bexarotene  Treatment of cutaneous T-cell lymphomas
14.05.02 Bezlotoxumab  Prevention of recurrence of Clostridium difficile infection
08.03.04.02 Bicalutamide  Treatment of advanced prostate cancer
11.06 Bimatoprost 100 micrograms/ml eye drops 

Treatment of glaucoma

SecondLine-

11.06 Bimatoprost 300 micrograms/ml eye drops 

Treatment of glaucoma

SecondLine-

11.06 Bimatoprost 300 micrograms/ml with Timolol 0.5% eye drops 

Treatment of glaucoma

SecondLine-

11.06 Bimatoprost 300 micrograms/ml with Timolol 0.5% eye drops 

 Treatment of glaucoma

Preferred-

09.08.01 Biotin (Vitamin H)  Treatment of isolated carboxylase defects and defects of biotin metabolism
06.01.01.02 Biphasic Insulin Aspart NovoMix® 30
06.01.01.02 Biphasic Insulin Lispro Humalog® Mix
06.01.01.02 Biphasic Isophane Insulin Humulin® M3
02.04 Bisoprolol tablets 
02.04 Bisoprolol tablets 

Treatment of moderate to severe heart failure

Preferred-

02.08.01 Bivalirudin  Anticoagulation in patients undergoing percutaneous coronary intervention and treatment of unstable angina/non-ST segment elevation myocardial infarction
08.01.02 Bleomycin  Treatment of metastatic germ cell cancer, non-Hodgkins lymphoma and squamous cell carcinoma
08.02 Blinatumomab  Treatment of adults with Philadelphia chromosome negative relapsed or refractory B-precursor acute lymphoblastic leukaemia
05.03.03.02 Boceprevir  Part of combination treatment of chronic hepatitis genotype 1 infection
08.01.05 Bortezomib  Treatment of multiple myeloma and mantle cell lymphoma
02.05.01 Bosentan  Treatment of pulmonary arterial hypertension and to reduce the number of new digital ulcers in patients with systemic sclerosis and ongoing digital ulcer disease
04.07.04.02 Botulinum toxin A Botox®

Prophylaxis of chronic migraine headaches

Prescribe by brand as products not interchangeable

04.09.03 Botulinum toxin A Azzalure®, Bocouture®, Botox®, Vistabel®, Dysport®, Xeomin®

Treatment of focal spasticity, spasmodic torticollis, blepharospasm, hemifacial spasm, post stroke spasticity of the upper limb, temporary improvement in the appearance of facial lines

Prescribe by brand as products not interchangeable

07.04.02 Botulinum toxin A  Botox® Treatment of bladder dysfunction

prescribe by brand as products not interchangeable

04.09.03 Botulinum toxin B NeuroBloc® Treatment of cervical dystonia
08.01.05 Brentuximab vedotin  Treatment of relapsed or refractory CD30+ Hodgkin’s lymphoma and treatment of relapsed or refractory systemic anaplastic large cell lymphoma
11.06 Brimonidine 0.2% eye drops  Use as third line - Treatment of glaucoma
11.06 Brimonidine Tartrate 0.2% with Timolol 0.5% eye drops 

Treatment of glaucoma

SecondLine-

11.06 Brinzolamide 1% & brimonidine 0.2% eye drops 

Treatment of glaucoma

SecondLine-

11.06 Brinzolamide 1% eye drops 

Treatment of glaucoma

SecondLine-

11.06 Brinzolamide 1% with Timolol 0.5% eye drops 

Treatment of glaucoma

SecondLine-

04.08.01 Brivaracetam injection  Adjunctive therapy in the treatment of partial-onset seizures
04.08.01 Brivaracetam oral  Adjunctive therapy in the treatment of partial-onset seizures
13.05.03 Brodalumab injection 

Treatment of moderate to severe plaque psoriasis in adult patients who are candidates for systemic therapy

11.08.02 Bromfenac eye drops  Treatment of postoperative ocular inflammation following cataract extraction
06.07.01 Bromocriptine  Prevention or suppression of lactation, hypogonadism, acromegaly, prolactinoma, menstrual cycle disorders
03.02 Budesonide Easyhaler®
03.02 Budesonide & formoterol 100/6 Symbicort® Turbohaler
03.02 Budesonide & formoterol 160/4.5 DuoResp® Spiromax
03.02 Budesonide & formoterol 200/6 Symbicort® MDI
03.02 Budesonide & formoterol 200/6, 400/12  Symbicort® Turbohaler
03.02 Budesonide & formoterol 320/9 DuoResp® Spiromax
01.05.02 Budesonide oral  Induction of remission in Crohn's disease and collagenous colitis, induction and maintenance of remission of autoimmune hepatitis
01.05.02 Budesonide rectal  Treatment of active ulcerative colitis limited to the rectum and the sigmoid colon
02.02.02 Bumetanide tablets  Treatment of oedema
15.02 Bupivacaine Hydrochloride  Production of local anaesthesia by percutaneous infiltration, peripheral nerve blocks and central neural block
15.02 Bupivacaine with Fentanyl  Maintenance of analgesia post-operatively and maintenance of epidural analgesia during labour
04.10.03 Buprenorphine 

Treatment of opioid dependence

Specialist to provide a share care agreement as required

04.07.02 Buprenorphine patch 

For nociceptive and neuropathic pain further information refer to APC CG003 guidance in yellow section below 

Strong opioids not generally of benefit for neuropathic pain

Prescribe as Butec or Reletrans cost effective brand

06.07.02 Buserelin  Treatment of endometriosis
06.07.02 Buserelin  Treatment of Infertility
08.03.04.02 Buserelin  Treatment of prostate cancer
04.01.02 Buspirone tablets  Longer term use
08.01.01 Busulfan  Chronic Myeloid Leukemia, conditioning treatment before haematopoietic stem-cell transplantation

08.01.05 Cabaziltaxel  Treatment of prostate cancer
06.07.01 Cabergoline  Treatment of hyperprolactinaemia
08.01.05 Cabozantinib  Treatment of renal and thyroid cancer
13.05.02 Calcipotriol with Betamethasone  Enstilar®

Topical treatment of psoriasis vulgaris in adults

The recommended treatment period is 4 weeks therefore not for repeat prescription

13.05.02 Calcipotriol with Betamethasone  Dovobet®

Topical treatment of stable plaque psoriasis vulgaris in adults

 

06.06.01 Calcitonin   Prevention of acute bone loss due to sudden immobilisation
06.06.01 Calcitonin   Treatment of Paget's Disease
08.01 Calcium Folinate  Prevention of methotrexate adverse effects and with fluorouracil in cytotoxic therapy
08.01 Calcium Leofolinate  To diminish toxicity and counteract the action of folic acid antagonists such as methotrexate and for use with florouracil for colorectal cancer
06.01.02.03 Canagliflozin  Treatment of Type 2 diabetes when used with insulin
08.02.04 Canakinumab  Treatment for all licensed indications
02.05.05.02 Candesartan tablets 
02.09 Cangrelor  Reduction of thrombotic cardiovascular events in patients with coronary artery disease undergoing percutaneous coronary intervention
08.01.03 Capecitabine  Treatment for all licensed indications
05.01.09 Capreomycin  In combination with other drugs, tuberculosis resistant to first-line drugs
04.07.03 Capsaicin cutaneous patch  Treatment of peripheral neuropathic pain
02.05.05.01 Captopril 50 mg tablets TDS  Overt nephropathy in Type 1 diabetes mellitus
04.02.03 Carbamazepine 
04.07.03 Carbamazepine 
04.08.01 Carbamazepine  Treatment of epilepsy - MHRA advises prescribing by brand to avoid loss of seizure control by switching brands

07.01.01 Carbetocin  Prevention of uterine atony after caesarean section.
06.02.02 Carbimazole 

Treatment of hyperthyroidism

Preferred-

11.08.01 Carbomer 0.2% gel Clinitas Carbomer Gel® In use expiry is 28 days
11.08.01 Carbomer 0.2% gel Xailin Gel® In use expiry is 28 days
08.01.05 Carboplatin  Treatment of advanced ovarian cancer and lung cancer
07.01.01 Carboprost  Treatment of post-partum haemorrhage due to uterine atony and refractory to conventional methods of treatment
04.09.01 Careldopa/entacapone/levodopa 

Treatment of Parkinson's disease

Prescribe as Stanek or Sastravi cost effective brand

SecondLine-

08.01.05 Carfilzomib  In combination with lenalidomide and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy
09.08.01 Carglumic Acid  Treatment of hyperammonaemia
11.08.01 Carmellose 0.5% & 1% eye drops Cellusan Light®, Cellusan® Multi-dose 10ml preservative free bottle, in use expiry - 90 days
11.08.01 Carmellose 0.5% & 1% unit dose vials Xailin Fresh®,Cellusan® Preservative free
08.01.01 Carmustine implant  Treatment of glioma and recurrent glioblastoma multiforme

02.04 Carvedilol tablets 

Adjunct in the treatment of heart failure

Preferred-

05.02.04 Caspofungin infusion  Treatment of invasive aspergillosis and invasive candidiasis, empirical treatment of systemic fungal infections in patients with neutropenia
08.02.03 Catumaxomab  Treatment of malignant ascites in patients with epithelial cell adhesion molecule positive carcinomas
05.01.02.01 Cefotaxime  Treatment of serious infections and pre-operative prophylaxis
05.01.02.01 Ceftaroline  Treatment of complicated skin and soft tissue infections and community-acquired pneumonia
05.01.02.01 Ceftazidime  Treatment of upper and lower respiratory tract infections
05.01.02.01 Ceftazidime/avibactam  Treatment of bacterial infections in line with local antibiotic guidelines
05.01.02.01 Ceftobiprole  Treatment of hospital and community acquired pneumonia
05.01.02 Ceftolozane & tazobactam  Treatment of complicated intra-abdominal infections, acute pyelonephritis, complicated urinary tract infections
05.01.02.01 Ceftriaxone  Treatment of pneumonia, septicaemia, skin and soft tissue infections, infections in neutropenic patients, peri-operative prophylaxis
05.01.02.01 Ceftriaxone intramuscular injection  Treatment of pelvic inflammatory disease with doxycycline and metronidazole.
Treatment of bacterial meningitis if allergy to penicillins, but caution in severe allergy
05.01.02.01 Cefuroxime  Treatment of infections and surgical prophylaxis
11.03.01 Cefuroxime eye drops   Treatment of bacterial eye infections
11.08.02 Cefuroxime intracameral injection Aprokam® Prophylaxis after cataract surgery
08.01.05 Ceritinib  Treatment of non-small cell lung cancer
10.01.03 Certolizumab Pegol 

Treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylosis

03.04.01 Cetirizine 1 mg/ml oral solution sugar free  Swallowing difficulties
03.04.01 Cetirizine tablets 
06.07.02 Cetrorelix  Treatment of female infertility
08.01.05 Cetuximab  Treatment of head and neck cancer and colorectal cancer

08.01.01 Chlorambucil  Treatment of lymphomas and chronic leukaemias
11.03.01 Chloramphenicol 0.5% eye drops   Bacterial conjunctivitis, most bacterial episodes are self limiting
11.03.01 Chloramphenicol 0.5% eye drops   Bacterial conjunctivitis, most bacterial episodes are self limiting
11.03.01 Chloramphenicol 1% eye ointment  Treatment of bacterial eye infections
05.01.07 Chloramphenicol oral & injection 

Treatment of life threatening infections

11.03.01 Chlorhexidine 0.02% eye drops   Treatment of protozoal eye infection in combination with one other agent
15.02 Chloroprocaine hydrochloride   Intrathecal anaesthesia
10.01.03 Chloroquine 

Treatment of discoid and systemic lupus erythematosus and rheumatoid arthritis

03.04.01 Chlorphenamine tablets 
04.02.01 Chlorpromazine 

Treatment of childhood schizophrenia and autism

SecondLine-

04.02.01 Chlorpromazine  

Schizophrenia and other psychoses (especially paranoia), mania and hypomania. In anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour. Induction of hypothermia

SecondLine-

02.02.01 Chlortalidone tablets 
17 Cholesterol Powder  Treatment of Smith-Lemli-Opitz syndrome
01.09.01 Cholic acid   Treatment of inborn errors in primary bile acid synthesis
06.05.01 Choriogonadotropin Alfa  Treatment of infertility
06.05.01 Chorionic gonadotrophin  Treatment of infertility
08.02.02 Ciclosporin 

Suppression of renal transplant rejection & nephrotic syndrome

10.01.03 Ciclosporin  Rheumatoid arthritis
Must prescribe by brand
13.05.03 Ciclosporin  Psoriasis and atopic dermatitis

Must prescribe by brand
11.04.02 Ciclosporin eye drops Ikervis® Treatment of severe keratitis in adult patients with dry eye disease
05.03.02.02 Cidofovir   Cytomegalovirus retinitis in AIDS patients
09.05.01.02 Cinacalcet Mimpara® Secondary hyperparathyroidism in patients with end-stage renal disease on dialysis
05.01.12 Ciprofloxacin  Treatment of infections in line with hospital antibiotic guidelines
11.03.01 Ciprofloxacin 0.3% eyedrops  Treatment of bacterial eye infections
11.03.01 Ciprofloxacin 3mg/g eye ointment  Treatment of bacterial eye infections
05.01.12 Ciprofloxacin oral  Only for the treatment of acute pyelonephritis and acute prostatitis
If allergy to penicillin: use with clindamycin for animal bites and with metronidazole for diverticulitis
15.01.05 Cisatracurium  Neuromuscular blockade during surgery, intubation and intensive care
08.01.05 Cisplatin  Treatment of testicular, lung, cervical, bladder, head and neck, and ovarian cancer
04.03.03 Citalopram oral drops  Swallowing difficulties
04.03.03 Citalopram tablets 
08.01.03 Cladribine  Treatment of hairy cell leukaemia and B-cell chronic lymphocytic leukaemia
08.01.03 Cladribine tablets Mavenclad®

Relapsing-remitting multiple sclerosis

05.01.05 Clarithromycin oral  Treatment of community acquired pneumonia, cellulitis, impetigo and non severe wound infections, acute otitis media or otitis externa, pharyngitis/tonsillitis where antibiotics necessary, if allergy to penicillins. For treatment of tooth abcess if allergy to penicillins and only when dentist unavailable. Part of Helicobacter pylori eradication
05.01.06 Clindamycin oral 

Treatment of cellulitis, or human and animal bites with ciprofloxacin, if allergy to penicillins. For a 450mg dose, 3 x 150 mg most cost effective

Preferred-

07.02.02 Clindamycin cream  Treatment of bacterial vaginosis
05.01.06 Clindamycin Injection  Treatment of serious infections
05.01.06 Clindamycin oral  Treatment of serious infections, for a 450mg dose, 3 x 150 mg most cost effective
04.08.01 Clobazam  Treatment of epilepsy
08.01.03 Clofarabine  Treatment of acute lymphoblastic leukemia
- unlicensed treatment of acute myeloblastic leukemia CDF

05.01.10 Clofazimine  Treatment of leprosy
04.01.01 Clomethiazole capsules  In the elderly
06.05.01 Clomifene Citrate  Treatment of anovulatory infertility
04.03.01 Clomipramine capsules 
04.08.01 Clonazepam  Treatment of epilepsy
04.04 Clonidine  Treatment of attention deficit hyperactivity disorder and tics in children
02.09 Clopidogrel 
07.02.02 Clotrimazole  Treatment of vaginal candidiasis
500mg pessary, PLUS cream if co-existing vulvitis
13.10.02 Clotrimazole  Treatment of vaginal candidiasis
500mg pessary, plus cream if co-existing vulvitis
04.02.01 Clozapine 

Treatment of resistant schizophrenia

Preferred-

05.01.01.03 Co-Amoxiclav oral  Only for treatment of animal and human bites and diverticulitis
04.09.01 Co-beneldopa controlled release 

Treatment of Parkinson's disease

SecondLine-

04.09.01 Co-beneldopa immediate release 

Treatment of Parkinson's disease

Preferred-

08.02.04 Cobimetinib  Treatment of unresectable or metastatic melanoma with a BRAF V600 mutation

04.09.01 Co-careldopa controlled release 

Treatment of Parkinson's disease

SecondLine-

04.09.01 Co-careldopa immediate release 

Treatment of Parkinson's disease

Preferred-

04.07.02 Codeine oral 

For nociceptive pain

Refer to APC CG003 guidance in yellow section below

09.06.04 Colecalciferol & calcium carbonate tablet Accrete D3® Each tablet contains 1.5 gram calcium carbonate and 400 units colecalciferol
Swallow tablet whole
09.06.04 Colecalciferol & calcium carbonate caplet Adcal-D3® Each caplet contains 750 mg calcium carbonate & 200 units colecalciferol
Swallow caplet whole
09.06.04 Colecalciferol & calcium carbonate chewable tablet Calci-D® Each tablet contains 2.5 gram calcium carbonate and 1,000 units colecalciferol
09.06.04 Colecalciferol & calcium carbonate chewable tablet Evacal D3® Each tablet contains 1.5 gram calcium carbonate & 400 unit colecalciferol
09.06.04 Colecalciferol 20,000 units capsules Plenachol®, Avitcol®,
09.06.04 Colecalciferol 25,000 unit liquid Invita D3®
09.06.04 Colecalciferol 50,000 unit liquid Invita D3®
02.12 Colesevelam Cholestagel® Bile acid malabsorption
05.01.07 Colistimethate for nebulisation/inhalation 

Inhalation therapy as an adjunct to standard antibacterial therapy in cystic fibrosis - all new patients

05.01.07 Colistimethate for nebulisation/inhalation 

Inhalation therapy as an adjunct to standard antibacterial therapy in cystic fibrosis. Existing patients until repatriated to secondary care

10.03.01 Collagenase 

Treatment of Dupuytren's contracture and Peyronie's disease

03.04.03 Conestat Alfa  Treatment of acute angioedema attacks in hereditary angioedema due to C1 esterase inhibitor deficiency
06.05.01 Corifollitropin Alfa  Controlled ovarian stimulation
13.02.01 Creams & lotions e.g. Cetraben®, Aquamax®, Zerobase®,Zerocream®,
08.01.05 Crisantaspase   Treatment of acute lymphoblastic leukaemia
11.05 Cyclopentolate 0.5% & 1% eye drops 
11.05 Cyclopentolate 1% eye drops  
08.01.01 Cyclophosphamide  Treatment of malignant disease
05.01.09 Cycloserine  Treatment of tuberculosis resistant to first-line drugs, in combination with other drugs
08.03.04.02 Cyproterone  Treatment of prostate cancer
06.04.02 Cyproterone Acetate Androcur® Treatment of hypersexuality and sexual deviation in males
08.01.03 Cytarabine  Treatment of leukaemias
08.01.03 Cytarabine  Treatment of lymphomatous meningitis
02.08.02 Dabigatran 

Treatment and prevention of thromboembolic events, and stroke prevention in atrial fibrillation

Specialist to complete SIDC

02.08.02 Dabigatran  Prophylaxis of venous thromboembolism following knee or hip surgery -
full course to be given post operation by provider

08.01.05 Dabrafenib  Treatment of unresectable or metastatic melanoma with a BRAF V600 mutation
08.01.05 Dacarbazine  Treatment of melanoma, sarcomas and Hodgkin's Disease
05.03.03.02 Daclatasvir  

Treatment of chronic hepatitis C

08.02.02 Daclizumab  Treatment of relapsing forms of multiple sclerosis
08.01.02 Dactinomycin  Treatment of cancers, principally paediatric
02.08.01 Dalteparin  Surgical prophylaxis
02.08.01 Dalteparin  Prophylaxis and treatment of thrombosis and embolism in pregnancy - see links below
02.08.01 Dalteparin  In most scenarios (e.g. DVT prophylaxis in surgical settings)
LMWHs are within tariff and therefore acute provider should supply
02.08.01 Danaparoid  Prevention of deep vein thrombosis in general or orthopaedic surgery.Treatment of thrombo-embolic disorders in history of heparin-induced thrombocytopenia
10.02.02 Dantrolene  Treatment of chronic severe spasticity of voluntary muscle
15.01.08 Dantrolene injection  Treatment of malignant hyperthermia
06.01.02.03 Dapagliflozin  Treatment of Type 2 diabetes when used with insulin
07.04.05 Dapoxetine  Treatment of premature ejaculation - see link below for prescribing advice
05.01.10 Dapsone  Treatment of leprosy and dermatitis herpeformis
05.01.07 Daptomycin  Treatment of complicated skin and soft tissue infections and endocarditis caused by gram-positive bacteria
08.02.03 Daratumumab  Treatment of relapsed and refractory multiple myeloma
09.01.03 Darbepoetin Alfa  Treatment of anaemia in cancer patients receiving chemotherapy

Treatment of renal anaemia: locally, supplies provided by secondary care
Outside area: SC may be required

05.03.01 Darunavir  Treatment of HIV infection in combination with other antiretroviral drugs
05.03.01 Darunavir & cobicistat  Treatment of HIV infection in combination with other antiretroviral drugs

08.01.05 Dasatinib  Treatment of leukaemia
08.01.03 Decitabine  Treatment of acute myeloid leukaemia
09.01.03 Deferasirox  Treatment of transfusion related iron overload in thalassaemia major or other anaemias
09.01.03 Deferiprone Ferriprox® Treatment of iron overload in thalassaemia major

08.03.04.02 Degarelix Firmagon® Treatment of advanced hormone-dependent prostate cancer
06.06.02 Denosumab  Treatment of post menopausal osteoporosis.

Specialist to complete SIDC
06.06.02 Denosumab  Reduction of bone damage in patients with metastases from solid tumours
09.01.03 Desferrioxamine Mesilate  Treatment of iron poisoning or overload, and aluminium overload in dialysis patients
15.01.02 Desflurane  Maintenance of anaesthesia
06.05.02 Desmopressin  Treatment of diabetes insipidus, nocturia, posthypophysectomy, mild to moderate haemophilia and Von Willebrand’s disease
11.04.01 Dexamethasone 0.1% eye drops 
11.04.01 Dexamethasone 0.1% eye drops  
11.04.01 Dexamethasone intravitreal implant Ozurdex®

Treatment of macular oedema (retinal vein occlusion, diabetic macular oedema and uveitis

11.04.01 Dexamethasone/neomycin/polymyxin B 
04.04 Dexamfetamine  Use as third line for management of attention deficit hyperactivity disorder
15.01.04.04 Dexmedetomidine   Maintenance of sedation during intensive care
08.01 Dexrazoxane  Treatment of anthracycline extravasation and prevention of cumulative anthracycline cardiotoxicity
04.07.02 Diamorphine injection  For use in syringe drivers
04.07.02 Diamorphine subcut injection 

For pain control in palliative care

Refer to APC CG040 guidance in yellow section below

04.01.02 Diazepam  Short term use only
Avoid oral solution
06.01.04 Diazoxide tablets  Treatment of chronic intractable hypoglycaemia
10.03.02 Diclofenac 
11.08.02 Diclofenac 0.1% eye drops  Inhibition of peroperative miosis , treatment of post-operative ocular inflammation and control of ocular pain after surgery or accidental non-penetrating trauma
10.01.01 Diclofenac tablets  If no CV risk and for short term use only (not for repeat prescription)
05.03.01 Didanosine  HIV infection in combination with other antiretroviral drugs
05.05 Diethylcarbamazine   Treatment of microfilariae and adults of Loa loa, Wuchereria bancrofti, and Brugia malayi
08.03.01 Diethylstilbestrol  Treatment of prostate cancer
02.01.01 Digoxin elixir  Treatment of heart failure and atrial fibrillation and flutter
use liquid for swallowing difficulties
02.01.01 Digoxin injection 

 Emergency parenteral digitilisation

02.01.01 Digoxin specific antibody fragments DigiFab® Life threatening digoxin toxicity
02.01.01 Digoxin tablets 
04.07.02 Dihydrocodeine 

For nociceptive pain

Refer to APC CG003 guidance in yellow section below

04.07.02 Dihydrocodeine injection  Relief of severe pain
04.07.02 Dihydrocodeine MR  For nociceptive pain refer to APC guidance above
05.04.02 Diloxanide  Treatment of amoebiasis
02.06.02 Diltiazem modified release   Intolerance/adverse reactions to amlodipine


Advice:
Prescribe modified release by brand, consult prescribing advisor for most cost effective brands

08.02.04 Dimethyl fumarate Tecfidera®

Treatment of relapsing remitting multiple sclerosis

13.05.02 Dimethyl Fumarate Skilarence ®

Treatment of moderate to severe plaque psoriasis

07.01.01 Dinoprostone  Cervical ripening and induction of labour
02.09 Dipyridamole modified release 
11.99.99.99 Disodium edetate 0.37%   Opthalmology use only
08.01 Disodium Folinate  Antidote to methotrexate and adjunct to fluorouracil for colorectal cancer
06.06.02 Disodium Pamidronate  Treatment of hypercalcaemia of malignancy, osteolytic lesions and bone pain in bone metastases and Paget's disease of bone
02.03.02 Disopyramide  Treatment of cardiac arrhythmias
04.10.01 Disulfiram Antabuse® Adjunct in the treatment of chronic alcohol dependence (under medical supervision).
02.07.01 Dobutamine  Inotropic support and cardiac stress testing
08.01.05 Docetaxel  Treatment of cancer



05.03.01 Dolutegravir  HIV infection in combination with other antiretroviral drugs
04.06 Domperidone oral 

Used for nausea and vomiting in palliative care

Refer to APC CG040 guidance

04.11 Donepezil tablets 

Mild to moderate dementia in Alzheimer's disease

Preferred-

02.07.01 Dopamine  Treatment of cardiogenic shock in infarction or cardiac surgery
02.07.01 Dopexamine  Inotropic support and vasodilator in exacerbations of chronic heart failure and in heart failure associated with cardiac surgery
03.07 Dornase alfa  Management of cystic fibrosis
11.06 Dorzolomide 2% eye drops 

Treatment of glaucoma

SecondLine-

11.06 Dorzolomide 2% eye drops   Use as third line - Treatment of glaucoma
11.06 Dorzolomide 2% with Timolol 0.5% eye drops 

Treatment of glaucoma

SecondLine-

11.06 Dorzolomide 2% with Timolol 0.5% eye drops 

Treatment of glaucoma

Preferred-

03.05.01 Doxapram  Treatment of acute respiratory failure and postoperative respiratory depression
07.04.01 Doxazosin tablets  standard release only
08.01.02 Doxorubicin  Treatment of leukemia's, lymphomas, ovarian and breast cancer, Karposi's sarcoma and also, of bladder cancers by bladder instillation
05.01.03 Doxycycline oral  Treatment of Chlamydia trachomatis and in combination treatment of Pelvic Inflammatory Disease, and sinusitis and COPD if allergy to penicillins For skin infections where MRSA likely cause - review with sensitivities and discuss with microbiologist
02.11 Dried prothrombin complex  Treatment and prophylaxis of bleeding in deficiency of prothrombin complex coagulation factors and any of the vitamin K dependent coagulation factors
02.03.02 Dronedarone  Clinically stable patients with previous or current non-permanent AF
06.01.02.03 Dulaglutide 

Treatment of type 2 diabetes mellitus

Preferred-

04.07.03 Duloxetine  Use as third line: Licensed for diabetic neuropathy only but potential for use outside of license in line with NICE
04.03.04 Duloxetine capsules 
09.01.03 Eculizumab  Treatment of paroxysmal nocturnal haemoglobinuria
02.08.02 Edoxaban 

Treatment and prevention of thromboembolic events, and stroke prevention in atrial fibrillation

Specialist to complete SIDC

02.08.02 Edoxaban  Prophylaxis of venous thromboembolism following knee or hip surgery -
full course to be given post op by provider
05.03.01 Efavirenz  HIV infection in combination with other antiretroviral drugs.
09.01 Efmoroctocog alfa  Treatment and prophylaxis of bleeding in haemophilia A (congenital factor VIII deficiency)
02.11 Eftrenonacog alfa  Treatment and prophylaxis of bleeding in haemophilia B (congenital factor IX deficiency)
05.03.03.02 Elbasvir-grazoprevir  Treatment of chronic hepatitis C
09.08.01 EliglustatRestricted Item  Long-term treatment of adult patients with Gaucher disease type 1 (GD1)
09.08.01 Elosulfase alpha  Treatment of mucopolysaccharidosis type IVa
08.01.05 Elotuzumab  Treatment of multiple myeloma
09.01.04 Eltrombopag 

Treatment of thrombocytopenia

01.04.02 Eluxadoline Truberzi®

Treatment of irritable bowel syndrome with diarrhoea (IBS-D) in adults

13.02.01.01 Emollients - Bath & Shower e.g.Aquamax®, Dermalo®

Maximum of 500ml per month

Advise to continue using standard emollients

 

06.01.02.03 Empagliflozin  Treatment of Type 2 diabetes when used with insulin
05.03.01 Emtricitabine  HIV infection in combination with other antiretroviral drugs
02.05.05.01 Enalapril  
05.03.01 Enfuvirtide Fuzeon® HIV infection in combination with other antiretroviral drugs
02.08.01 Enoxaparin  Surgical prophylaxis
02.08.01 Enoxaparin  In most scenarios (e.g. DVT prophylaxis in surgical settings)
LMWHs are within tariff and therefore acute provider should supply
02.08.01 Enoxaparin  Prophylaxis and treatment thrombosis and embolism in pregnancy - see links below
02.01.02 Enoximone  Treatment of congestive heart failure
04.09.01 Entacapone 

Treatment of Parkinson's disease

SecondLine-

05.03.03.01 Entecavir  Treatment of chronic hepatitis B
08.03.04.02 Enzalutamide  Treatment of prostate cancer
02.07.02 Ephedrine injection  Reversal of low blood pressure resulting from spinal or epidural anaesthesia
08.01.02 Epirubicin   Treatment of breast cancer and treatment and prophylaxis of superficial bladder cancer
02.02.03 Eplerenone  Adjunct in stable patients with left ventricular dysfunction with evidence of heart failure, following myocardial infarction, adjunct in chronic mild heart failure
09.01.03 Epoetin alfa  Treatment of anaemia in cancer patients receiving chemotherapy

Treatment of renal anaemia: locally, supplies provided by secondary care
Outside area: SC may be required

09.01.03 Epoetin beta  Treatment of anaemia in cancer patients receiving chemotherapy

Treatment of renal anaemia: locally, supplies provided by secondary care
Outside area: SC may be required

09.01.03 Epoetin zeta  Treatment of anaemia in cancer patients receiving chemotherapy

Treatment of renal anaemia: locally, supplies provided by secondary care
Outside area: SC may be required

02.08.01 Epoprostenol (prostacyclin)  Inhibition of platelet aggregation during renal dialysis and treatment of primary pulmonary hypertension resistant to other treatments
20 Eprodisate   Treatment of Amylois A amyloidosis
02.09 Eptifibatide Integrilin® Prevention of early myocardial infarction in unstable angina or non-ST-segment-elevation myocardial infarction
03.07 Erdosteine  Symptomatic treatment of acute exacerbations of chronic bronchitis
09.06.04 Ergocalciferol  Oral vitamin D3 (Colecalciferol) is recommended over other forms of vitamin D.
However, oral Ergocalciferol may be appropriate for vegan patients, and Ergocalciferol IM injection may be used where oral absorption is poor
08.03.04.01 Eribulin 

Treatment of breast cancer

08.01.05 Erlotinib  Treatment of non-small-cell lung and pancreatic cancer
05.01.02.02 Ertapenem  Treatment of abdominal infections, acute gynaecological infections, community-aquired pneumonia, diabetic foot infections of the skin and soft-tissue, prophylaxis for colorectal surgery
11.03.01 Erythromycin eye ointment  Treatment of bacterial eye infections
04.03.03 Escitalopram tablets  10% dearer than citalopram
04.08.01 Eslicarbazepine  Treatment of epilepsy
02.04 Esmolol  Treatment of supraventricular arrhythmias and peri-operative tachycardia and hypertension
08.01.01 Estramustine Phosphate Estracyt® Treatment of prostate cancer
10.01.03 Etanercept 

Treatment of rheumatoid, juvenile idiopathic and psoriatic arthritis and ankylosing spondylitis

13.05.03 Etanercept 

Treatment of severe psoriasis

09.05.01.02 EtelcalcetideRestricted Item  Secondary hyperparathyroidism in patients with chronic kidney disease on haemodialysis
05.01.09 Ethambutol   Treatment of tuberculosis, in combination with other drugs
06.04.01.01 Ethinylestradiol 2 micrograms  Induction of sexual maturation in girls
04.08.01 Ethosuximide  Treatment of epilepsy

15.01.01 Etomidate  Induction of anaesthesia
08.01.04 Etoposide  Small cell carcinoma of the bronchus, the lymphomas and testicular cancer
10.01.01 Etoricoxib  If intolerant to NSAID plus PPI - short term use only
05.03.01 Etravirine  HIV infection in combination with other antiretroviral drugs
08.01.05 Everolimus  Treatment of renal, breast and pancreatic cancer, renal angiomyelolipoma and subependymal giant cell astrocytoma
08.02.02 Everolimus  Prophylaxis of organ rejection following heart, renal or liver transplantation
02.12 Evolocumab 

Treatment of primary hypercholesterolaemia and mixed dyslipidaemia

08.03.04.01 Exemestane  Treatment of breast cancer
06.01.02.03 Exenatide Byetta▼®

Adjunct in the treatment of Type 2 diabetes

Preferred-

06.01.02.03 Exenatide prolonged release Bydureon▼®

Adjunct in the treatment of Type 2 diabetes

SecondLine-

02.12 Ezetimibe Ezetrol®
02.11 Factor VIIa recombinant with eptacog alfa  Treatment and prophylaxis of haemorrhage in patients with haemophilia A or B with inhibitors to factors VIII or IX, acquired haemophilia, factor VII deficiency, or Glanzmann’s thrombasthenia
02.11 Factor VIII Inhibitor Bypassing Fraction  Treatment and prophylaxis of haemorrhage in patients with congenital factor VIII deficiency (haemophilia A) and factor VIII inhibitors
Treatment of haemorrhage in non-haemophiliac patients with acquired factor VIII inhibitors
02.11 Factor XIII Fraction, Dried  Treatment of congenital Factor XIII deficiency
08.02.04 Fampridine  Improvement of walking disability in multiple sclerosis
06.01.01.01 Fast acting insulin aspart Fiasp Treatment of diabetes
10.01.04 Febuxostat Adenuric® True allopurinol intolerance only
04.07.02 Fentanyl immediate release sublingual tablets  Only for use in palliative care when short acting oral morphine ineffective and specific criteria met
See further details on the blacklisted indications below
15.01.04.03 Fentanyl injection  Analgesia during short surgical procedures and as a premedicant, analgesic/respiratory depressant in assisted ventilation, neuroleptanalgesia, treatment of severe pain
04.07.02 Fentanyl patches 

Swallowing difficulties.
Prescribe as Matrifen or Fencino cost effective brand

09.01.01.02 Ferric Carboxymaltose  Treatment of iron deficiency when oral iron preparations are ineffective or cannot be used
09.01.01.01 Ferrous Fumarate 210 mg tablets 
09.01.01.01 Ferrous Fumarate syrup  Swallowing difficulties
09.01.01.01 Ferrous Sulphate 200 mg tablets 
02.11 Fibrinogen  Treatment of haemorrhage in congenital hypofibrinogenaemia or afibrinogenaemia
05.01.07 Fidaxomicin  Treatment of Clostridium difficile infections
09.01.06 Filgrastim  Reduction and treatment of neutropenia and mobilization of peripheral blood progenitor cells
06.04.02 Finasteride tablets 
08.02.04 Fingolimod 

Treatment of highly active relapsing-remitting multiple sclerosis

06.01.06 Flash glucose monitoring system FreeStyle Libre®
02.03.02 Flecainide  Treatment of cardiac arrhythmias
05.01.01.02 Flucloxacillin oral  Treatment of cellulitis, impetigo and non severe wound infections. Treatment of otitis externa only if antibiotics necessary
05.02.05 Fluconazole infusion  Treatment of fungal infections, prophylaxis of crytopcoccal meningitis, oropharyngeal or oesophageal candidiasis in HIV patients, candidal infections in prolonged neutropenia
07.02.02 Fluconazole oral  Treatment of vaginal candidiasis if failure to resolve with clotrimazole
05.02.05 Flucytosine  Treatment of systemic yeast and fungal infections and cryptococcal meningitis
08.01.03 Fludarabine Phosphate  Treatment of B-cell chronic lymphocytic leukaemia
06.03.01 Fludrocortisone  Partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome
15.01.07 Flumazenil  Reversal of sedative effects of benzodiazepines
04.07.04.01 Flunarizine 

Treatment of migraine

11.04.01 Fluocinolone intravitreal implant Iluvien®

Treatment of diabetic macular oedema

11.08.02 Fluorescein 2% eye drops  For diagnostic use
11.08.02 Fluorescein ophthalmic strips   For diagnostic use
11.04.01 Fluorometholone eye drops 
08.01.03 Fluorouracil iv/oral  Treatment of some solid tumours including gastro-intestinal tract cancers, breast cancer and colorectal cancer
13.08.01 Fluorouracil topical 

Treatment of superficial malignant and pre-malignant skin lesions and keratosis

13.08.01 Fluorouracil/salicylic acid topical solution  

Treatment of actinic keratosis

04.03.03 Fluoxetine 

For children and adolescents

Preferred-

04.03.03 Fluoxetine 20 mg capsules 
04.03.03 Fluoxetine 20 mg dispersible tablets   Swallowing difficulties
04.02.01 Flupentixol 
04.02.02 Flupentixol decanoate 

Treatment of schizophrenia and other psychoses

Preferred-

04.02.02 Fluphenazine decanoate 

Preferred-


Treatment of schizophrenia and other psychoses


note This (Modecate) injection is being permanently discontinued. Production will cease in mid-2018, and the product is expected to remain available in the UK up until the end of 2018. All presentations will be withdrawn (Modecate 25mg/ml and Modecate concentrate injection 100mg/ml)  - further information available on the APC newsfeed

03.02 Fluticasone furoate/umeclidinium/vilanterol Trelegy® Ellipta
03.02 Fluticasone furoate & vilanterol 184/22 Relvar Ellipta®
03.02 Fluticasone furoate & vilanterol 92/22 Relvar Ellipta®
03.02 Fluticasone propionate & formoterol 50/5, 125/5, 250/10  Flutiform® MDI
03.02 Fluticasone propionate & salmeterol 500/50 AirFluSal Forspiro®

Prescribe using the most cost effective brand

03.02 Fluticasone propionate & salmeterol 500/50 Aerivio Spiromax® Prescribe using the most cost effective brand
03.02 Fluticasone propionate & salmeterol MDI 125/25, 250/25  AirFluSal®

Prescribe using the most cost effective brand

12.02.01 Fluticasone propionate/Azelastine Dymista®

Use as third line - see allergic rhinitis treatment pathway

09.01.02 Folic acid 400 micrograms  

Prevention of neural tube defects in pregnancy

 

06.05.01 Follitropin Alfa   Treatment of infertility
06.05.01 Follitropin alpha with lutropin beta  Treatment of infertility
06.05.01 Follitropin Beta  Treatment of infertility
02.08.01 Fondaparinux sodium  Prophylaxis and treatment of venous thromboembolic events, treatment of unstable angina and ST-segment and non-ST-segment elevation myocardial infarction
03.01.01.01 Formoterol 12mcg easyhaler 
03.01.01.01 Formoterol 12mcg metered dose inhaler Atimos®
05.03.01 Fosamprenavir  Treatment of HIV infection
05.03.02.02 Foscarnet Sodium  Treatment of cytomegalovirus retinitis in AIDS patients and mucocutaneous herpes simplex virus infections
05.01.07 Fosfomycin infusion  Treatment of acute osteomyelitis, complicated urinary tract infections, nosocomial lower respiratory tract infections, bacterial meningitis and bacteraemia only when first line treatments are inappropriate or ineffective
05.01.07 Fosfomycin oral  Prophylaxis in diagnostic and surgical transurethral procedures
05.01.07 Fosfomycin oral  Treatment of acute lower uncomplicated urinary tract infections, caused by pathogens sensitive to fosfomycin in females
04.08.02 Fosphenytoin   Treatment of status epilepticus, seizures associated with neurosurgery or head injury, or when oral phenytoin not possible
08.03.04.01 Fulvestrant  Treatment of breast cancer
02.02.02 Furosemide injection 

 when immediate diuresis required

02.02.02 Furosemide liquid   Treatment of oedema and resistant hypertension
use liquid for swallowing difficulties
02.02.02 Furosemide tablets 
04.07.03 Gabapentin 
04.08.01 Gabapentin  Treatment of epilepsy
04.11 Galantamine modified release capsules Gatalin XL®

Mild to moderate dementia in Alzheimer's disease

Prescribe as Gatalin XL cost effective brand, this is more cost effective than standard release

Preferred-

09.08.01 Galsulfase  Treatment of Mucopolysaccharidosis VI
05.03.02.02 Ganciclovir  Treatment of cytomagalovirus infections
11.03.03 Ganciclovir 0.15% ophthalmic gel  Treatment of viral eye infections
06.07.02 Ganirelix  Treatment of female infertility
08.01.05 Gefitinib  Treatment of non-small cell lung cancer
12.03.01 Gelclair®  Mucositis resistant to standard treatments
08.01.03 Gemcitabine  Treatment of bladder, breast, ovarian, pancreatic and non-small-cell lung cancers
07.01.01 Gemeprost  Termination of pregnancy
11.03.01 Gentamicin 0.3% eye drops  Treatment of bacterial eye infections
11.03.01 Gentamicin 1.5% eye drops   Unlicensed preparation
05.01.04 Gentamicin injection  Treatment of bacteraemia,septicaemia, urinary-tract, chest, and other systemic infections due to sensitive organisms
06.07.02 Gestrinone  Treatment of endometriosis
08.02.04 Glatiramer Acetate  Treatment of multiple sclerosis
05.03.03.02 Glecaprevir-pibrentasvir Maviret®

Treatment of chronic hepatitis C

06.01.02.01 Gliclazide 80 mg tablets 
06.01.02.01 Glimepiride tablets 
A2.06.01 Gluten-Free Foods  

Applicable to: Coventry & Rugby & Warwickshire North CCG

11.08 Glycerol eye drops   Treatment of glaucoma
02.06.01 Glyceryl trinitrate injection  Reduction of blood pressure during surgical procedures, control of myocardial ischaemia during and after cardiovascular surgery, treatment of unresponsive congestive heart failure and unstable angina
02.06.01 Glyceryl Trinitrate Spray 
07.04.04 Glycine irrigation solution  Bladder irrigation during urological surgery
03.01.02 Glycopyrronium Seebri breezhaler®
15.01.03 Glycopyrronium bromide  Sialanar®

For the symptomatic treatment of severe sialorrhoea (chronic pathological drooling) in those with chronic neurological disorders

15.01.03 Glycopyrronium bromide injection  Pre-operative and intra-opearative antimuscarinic
01.03.06 Glycopyrronium bromide oral  Add-on therapy in the treatment of peptic ulcer
13.12 Glycopyrronium powder  Iontophoretic treatment of idiopathic hyperhidrosis
15.01.03 Glycopyrronium subcut injection 

Treatment of respiratory secretions in palliative care

Refer to APC CG040 guidance

 

01.05.03 Golimumab 

Treatment of ulcerative colitis

10.01.03 Golimumab 

Treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylosis

06.07.02 Goserelin  Treatment of endometriosis
06.07.02 Goserelin  Endometrial preparation prior to surgery

08.03.04.01 Goserelin  Treatment of breast cancer
08.03.04.02 Goserelin  Treatment of prostate cancer
04.06 Granisetron  Treatment in pregnancy, longer-term use in chemotherapy patients
04.06 Granisetron   Chemotherapy-induced nausea & vomiting maximum 5 days of therapy during treatment
Prevention of post-operative nausea & vomiting inpatient use only

03.04.02 Grass & Tree Pollen Extracts Pollinex® grass & rye, Pollinex® trees

Treatment of seasonal allergic hay fever due to grass and tree pollen

03.04.02 Grass pollen extract tablets Grazax® Treatment of seasonal allergic hay fever due to grass pollen in patients who have failed to respond to anti allergy drugs
04.04 Guanfacine XL tablets 

Treatment of Attention Deficit/Hyperactivity Disorder in children/adolescents 6 to 17 years of age

SecondLine-

A2.05.02 Gum based thickener Nutilis Clear®

Thickeners in sachet from should not be used and converted to tins

13.05.03 Guselkumab 

Treatment of moderate to severe plaque psoriasis in adults

 

09.08.02 Haem arginate (Human hemin) 
04.02.01 Haloperidol 

Childhood behavioural disorders, Gilles de la Tourette syndrome, childhood

Preferred-

04.02.01 Haloperidol 

Schizophrenia: treatment of symptoms and prevention of relapse, other psychoses: especially paranoid, mania and hypomania, mental or behavioural problems such as aggression, hyperactivity and self mutilation in the mentally retarded and in patients with organic brain damage, as an adjunct to short term management of moderate to severe psychomotor agitation, excitement, violent or dangerously impulsive behaviour, Gilles de la Tourette syndrome and severe tics

Preferred-

04.02.01 Haloperidol   First line use in CWPT - treatment of rapid control of the symptoms of hostility, aggression, hyperactivity, disruptive and violent behaviour, confusion, emotional withdrawal, hallucinations and delusions associated with acute and chronic schizophrenia, mania, and hypomania, and organic brain syndrome

04.02.02 Haloperidol decanoate 

Treatment of schizophrenia and other psychoses

Preferred-

04.06 Haloperidol subcut injection 
08.02.04 Histamine  Treatment of Acute Myeloid Leukaemia in combination with aldesleukin
03.04.03 Human C1-esterase inhibitor  Treatment and prophylaxis in hereditary angioedema
02.11 Human coagulation factor IX  Treatment and prophylaxis of bleeding in haemophilia B
(congenital factor IX deficiency)
02.11 Human coagulation factor VIII, octocog alpha  Treatment and prophylaxis of bleeding in patients with haemophilia A
(congenital factor VIII deficiency)
02.11 Human coagulation factor X  Treatment and prophylaxis in hereditary factor X deficiency
02.11 Human plasma protein  Treatment of coagulation factor deficiencies, rapid reversal of oral anticoagulants,haemorrhage treatment during fibrinolytic therapy, therapeutic plasma exchange
02.05.01 Hydralazine Injection  Treatment of hypertensive emergencies
06.03.02 Hydrocortisone standard release  Adrenal replacement therapy
04.07.02 Hydromorphone Hydrochloride  For the relief of severe pain in cancer. Use on advice of palliative care team
04.07.02 Hydromorphone injection  For the relief of severe pain in cancer
08.01.05 Hydroxycarbamide  Treatment of chronic myeloid leukaemia, and cancer of the cervix
09.01.03 Hydroxycarbamide (hydroxyurea)  Treatment of polycythemia and sickle cell anaemia
10.01.03 Hydroxychloroquine 

Treatment of rheumatoid arthritis, juvenile chronic arthritis, discoid and systemic lupus
erythermatosus

10.01 Hylan G-F 20  Treatment of pain in osteoarthritis of the knee
Not recommended by NICE
15.01.03 Hyoscine butylbromide subcut injection Buscopan®

Treatment of respiratory secretions in palliative care

Refer to APC CG040 guidance

 

11.08.01 Hypromellose 0.3% eye drops Evolve Hypromellose® Multi-dose preservative-free - 10ml bottle
3 month expiry
11.08.01 Hypromellose 0.3% eye drops Lumecare Tear Drops® Multi-dose preserved 10ml bottle - 28 day expiry
11.08.01 Hypromellose 0.3% unit dose vials Lumicare Singles® Preservative free
06.06.02 Ibandronic Acid 150mg tablets  

Monthly dose

06.06.02 Ibandronic Acid 50 mg tablets   Reduction of bone damage in bone metastases in breast cancer
06.06.02 Ibandronic Acid injection  Treatment of osteoporosis, hypercalcaemia of malignancy and reduction of bone metastases in breast cancer
08.01.05 Ibrutinib 

Treatment of chronic lymphocytic leukaemia & Waldenstrom's macroglobulinaemia

10.03.02 Ibuprofen gel 
10.01.01 Ibuprofen tablets 
03.04.03 Icatibant Firazyr® Treatment of hereditary angioedema in C1-esterase-inhibitor deficiency
08.01.02 Idarubicin   Treatment of leukaemias and breast cancer
02.08 Idarucizumab  Rapid reversal of anticoagulant effects of dabigatran etexilate
11.08 Idebenone tablet  Treatment of visual impairment in adolescent and adult patients with Leber's Hereditary Optic Neuropathy
08.01.05 Idelalisib 

Treatment of chronic lymphocytic leukaemia

09.08.01 Idursulfase  Treatment of mucopolysaccharidosis II
08.01.01 Ifosfamide  Treatment of malignant disease
02.05.01 Iloprost nebules  Treatment of pulmonary arterial hypertension
08.01.05 Imatinib  Treatment of leukaemias, gastrointestinal stromal tumours, dermatofibrosarcoma protuberans, and myelodysplastic/myeloproliferative diseases
09.08.01 Imiglucerase  Treatment of Gaucher's disease
04.07.03 Imipramine   Unlicensed indication
04.03.01 Imipramine tablets 
13.07 Imiquimod  Treatment of genital and perianal warts

13.08.01 Imiquimod   Treatment of basal cell carcinoma and actinic keratosis
03.01.04 Indacterol-Glycopyrronium inhaler Ultibro Breezhaler®
02.02.01 Indapamide standard release tablets 
01.05.03 Infliximab 

Treatment of Crohn’s disease and ulcerative colitis

10.01.03 Infliximab  Treatment of rheumatoid arthritis, psoriatric arthritis and ankylosing spondylitis
13.05.03 Infliximab 

Treatment of  plaque psoriasis

13.08.01 Ingenol mebutate gel 

Treatment of actinic keratosis

08.02 Inotuzumab ozogamicin 

Treatment of acute lymphoblastic leukaemia

06.01.01.02 Insulin degludec Tresiba® Treatment of diabetes mellitus
06.01.01.02 Insulin degludec & liraglutide Xultophy®

Treatment of type 2 diabetes mellitus to improve glycaemic control

06.01.01.02 Insulin Detemir Levemir®
06.01.01.02 Insulin Glargine Lantus®
06.01.01.02 Insulin Glargine biosimilar Abasaglar®
06.01.01.02 Insulin Glargine U300 Toujeo® Treatment of diabetes mellitus
06.01.01.01 Insulin Glulisine Apidra®
08.02.04 Interferon Alfa 

Treatment of hepatitis B

08.02.04 Interferon Beta  Treatment of multiple sclerosis
14.05 Interferon Gamma-1b Immukin® Reduction of serious infections in chronic granulomatous disease and malignant osteopetrosis
08.01.05 Ipilimumab  Treatment of melanoma
03.01.02 Ipratropium metered dose inhaler 
02.05.05.02 Irbesartan tablets  Nephropathy co-morbidity in diabetic patients
08.01.05 Irinotecan infusion 

Treatment of colorectal cancer

09.01.01.02 Iron dextran intravenous  Treatment of iron deficiency anaemia
09.01.01.02 Iron Isomaltoside  Treatment of iron deficiency anaemia
09.01.01.02 Iron Sucrose  Treatment of iron deficiency anaemia
05.02 Isavuconazole  Treatment of invasive aspergillosis and mucormycosis in patients for whom amphotericin B is inappropriate
15.01.02 Isoflurane  Induction and maintenance of general anaesthesia
05.01.09 Isoniazid 

Treatment of tuberculosis in combination with other drugs

05.01.09 Isoniazid 

TB prophylaxis for renal transplant patients as per BTS guidelines) (9 months)

06.01.01.02 Isophane Insulin Hypurin® Bovine Isophane
06.01.01.02 Isophane Insulin Insulatard®
06.01.01.02 Isophane Insulin Humulin® I
06.01.01.02 Isophane Insulin Insuman® Basal
02.06.01 Isosorbide Mononitrate MR 
02.06.01 Isosorbide Mononitrate standard release 
13.06.02 Isotretinoin oral  Acne vulgaris
02.06.03 Ivabradine  Treatment of angina in patients in normal sinus rhythm
03.07 Ivacaftor  Treatment of cystic fibrosis
05.05.06 Ivermectin   Treatment of onchocerciasis
05.05.07 Ivermectin   Treatment of cutaneous larva migrans

05.05.08 Ivermectin   Treatment of Strongyloides stercoralis
13.06 Ivermectin cream  Treatment of rosacea
13.10.04 Ivermectin cream  Treatment of scabies
08.01.05 Ixazomib 

Relapsed or refractory multiple myeloma

13.05.03 Ixekizumab 

Treatment of plaque psoriasis

15.01.01 Ketamine injection  Anaesthetic agent for diagnostic and surgical procedures
06.07 Ketoconazole 200 mg tablet Ketoconazole HRA®

Treatment of Endogenous Cushing's syndrome in adults and adolescents above the age of 12 years

11.08.02 Ketorolac 0.5% eye drops  Prophylaxis and reduction of inflammation and associated symptoms following ocular surgery
15.01.04.02 Ketorolac injection  Short-term management of moderate to severe acute post-operative pain
02.04 Labetalol injection  Treatment of severe hypertension when rapid control of blood pressure is essential, anaesthesia when a hypotensive technique is indicated and hypertensive episodes following acute myocardial infarction
02.04 Labetalol tablets  In pregnancy
04.08.01 Lacosamide   Adjunctive treatement of partial seizures with or without secondary generalisation
05.03.01 Lamivudine  HIV infection in combination with other antiretroviral drugs
05.03.01 Lamivudine 

Hepatitis B infection

Specialist to provide a share care agreement as required 

04.02.03 Lamotrigine 
04.08.01 Lamotrigine  Treatment of epilepsy
08.03.04.03 Lanreotide  Treatment of acromegaly, thyroid tumours and relief of symptoms of neuroendocrine tumours

01.03.05 Lansoprazole  Lansoprazole orodispersible - Swallowing difficulties, PEG tubes
01.03.05 Lansoprazole capsules 
09.05.02.02 Lanthanum Fosrenol ® Hyperphosphataemia in patients on haemodialysis or continuous ambulatory peritoneal dialysis (CAPD)
08.03.04.01 Lapatinib 

Treatment of breast cancer

09.08.01 Laronidase  Treatment of mucopolysaccharidosis 1
11.06 Latanoprost 50 micrograms/ml eye drops  

 Treatment of glaucoma

Preferred-

11.06 Latanoprost 50 micrograms/ml eye drops 

Treatment of glaucoma

SecondLine-

05.03.03.02 Ledipasvir-Sofosbuvir 

Treatment of chronic hepatitis C

10.01.03 Leflunomide 

Moderate to severe active rheumatoid arthritis; active psoriatic arthritis

08.02.04 Lenalidomide  Treatment of myelodysplastic syndrome, multiple myeloma and mantle cell lymphoma
09.01.06 Lenograstim  Reduction in duration of neutropenia and mobilisation of peripheral blood progenitor cells
08.01.05 Lenvatinib  Treatment of renal and thyroid cancer
02.06.02 Lercanidipine  Intolerance/adverse reactions to amlodipine

Advice: Prescribe modified release by brand, consult prescribing advisor for most cost effective brands

08.03.04.01 Letrozole  Treatment of breast cancer
06.07.02 Leuprorelin  Endometrial preparation prior to surgery
06.07.02 Leuprorelin  Treatment of endometriosis
08.03.04.02 Leuprorelin   Treatment of prostate cancer
05.05.02 Levamisole   Treatment of common roundworm infections when mebendazole cannot be used
04.08.01 Levetiracetam  Treatment of epilepsy
11.06 Levobunolol 0.5% eye drops 

Treatment of glaucoma

SecondLine-

15.02 Levobupivacaine  Management of post-operative pain and labour analgesia
09.08.01 Levocarnitine  Treatment of primary and secondary carnitine deficiency
04.09.01 Levodopa/carbidopa Duodopa® Fourth line option - Treatment of Parkinson's Disease
11.03.01 Levofloxacin 0.5% eye drops   Treatment of bacterial eye infections
05.01.12 Levofloxacin injection  Treatment of bacterial infections following advice from microbiologist
05.01.12 Levofloxacin nebuliser solution  Management of chronic pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis - all new patients
05.01.12 Levofloxacin nebuliser solution  Management of chronic pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis. Exisiting patients only until repatriated to secondary care
05.01.12 Levofloxacin oral  Treatment of bacterial infections following advice from microbiologist
06.02.01 Levothyroxine tablets  Treatment of hypothyroidism and hyperthyroidism (blocking-replacement regimen in combination with carbimazole)
15.02 Lidocaine injection  Intravenous regional anaesthesia and nerve blocks
02.03.02 Lidocaine intravenous injection  Treatment of ventricular arrhythmias
12.03.01 Lidocaine mouth spray  For the prevention of pain associated with various medical and surgical procedures
15.02 Lidocaine mouth spray  For the prevention of pain associated with various medical and surgical procedures
15.02 Lidocaine with Adrenaline  Regional anaesthesia
15.02 Lidocaine/phenylephrine topical solution  Anaesthesia before nasal surgery, endoscopy, laryngoscopy, or removal of foreign bodies from the nose
01.06.07 Linaclotide 

Treatment of moderate to severe IBS with constipation

See NICE guidance MTG36 below

06.01.02.03 Linagliptin tablets  In those with intolerance to alogliptin or sitagliptin/renal insufficiency
05.01.07 Linezolid  Treatment of pneumonia, complicated skin and soft tissue infections caused by Gram-positive bacteria
06.02.01 Liothyronine injection 

Treatment of myxoedema coma

SecondLine-

06.02.01 Liothyronine oral 

Treatment of coma of myxoedema, the management of severe chronic thyroid deficiency and hypothyroid states occurring in the treatment of thyrotoxicosis

SecondLine-

11.08.01 Liquid Paraffin eye ointment Xailin Night® Contains mineral and lanolin

Preservative free, in use expiry is 60 days

11.08.01 Liquid Paraffin eye ointment HydraMed Night® Contains retinol palmitate and wool fat

Preservative free, in use expiry is 90 days

04.05.02 Liraglutide  Saxenda®Restricted Item Treatment of obesity
Not approved for use at UHCW
06.01.02.03 Liraglutide  

Adjunct in the treatment of Type 2 diabetes

Preferred-

04.04 Lisdexamfetamine capsules 

Treatment of Attention Deficit Hyperactivity Disorder

SecondLine-

04.04 Lisdexamfetamine capsules 

Treatment of Attention Deficit Hyperactivity Disorder

Preferred-

02.05.05.01 Lisinopril tablets 
04.02.03 Lithium  Priadel®

Treatment and prophylaxis of mania, bipolar disorder and recurrent depression, aggressive or self mutilating behavior

Must prescribe by brand

Preferred-

04.02.03 Lithium Carbonate Camcolit®

Treatment and prophylaxis of mania, bipolar disorder and recurrent depression, aggressive or self mutilating behavior

Must prescribe by brand

SecondLine-

04.02.03 Lithium Carbonate Essential Pharma®

Treatment and prophylaxis of mania, bipolar disorder and recurrent depression, aggressive or self mutilating behavior

Must prescribe by brand

SecondLine-

06.01.02.03 Lixisenatide 

Adjunct in the treatment of Type 2 diabetes

Preferred-

11.04.02 Lodoxamide 0.1% eye drops 
04.03.01 Lofepramine tablets 
04.10.03 Lofexidine 

Management of symptoms of opioid withdrawal

Specialist to provide a share care agreement as required

02.12 Lomitapide  Adjunct to a low-fat diet and other lipid-lowering medicinal products with or without low density lipoprotein apheresis in adult patients with homozygous familial hypercholesterolaemia
08.01.01 Lomustine  Treatment of Hodgkins disease, malignant melanoma solid tumours
05.03.01 Lopinavir/ritonavir  Treatment of HIV infection in combination with other antiretroviral drugs
03.04.01 Loratadine 5 mg/5ml oral solution  Swallowing difficulties
03.04.01 Loratadine tablets 
04.01.02 Lorazepam  Short term use only
02.05.05.02 Losartan tablets 
11.04.01 Loteprednol 0.5% eye drops  Treatment of post-operative inflammation following ocular surgery
01.06.07 Lubiprostone 

Chronic idiopathic constipation and associated symptoms

See NICE guidance MTG36 below

04.02.01 Lurasidone 

Treatment of schizophrenia

SecondLine-

06.05.01 Lutropin Alfa  Treatment of infertility in women
02.05.01 Macitentan  Treatment of pulmonary arterial hypertension
01.06.05 Macrogols e.g. Moviprep®, Klean Prep®

Bowel cleansing preparation before surgery, surgical procedures or radiological examination.
Not treatments for constipation.

01.06.05 Magnesium citrate 

Bowel cleansing preparation before surgery, surgical procedures or radiological examination.
Not treatments for constipation.

09.05.01.03 Magnesium Sulphate  Treatment of acute hypomagnesaemia
02.02.05 Mannitol infusion  For use as an osmotic diuretic
03.07 Mannitol inhalation  Treatment of cystic fibrosis
05.03.01 Maraviroc  HIV infection in combination with other antiretroviral drugs
05.05.01 Mebendazole  Treatment of threadworm and ascaris (roundworm)
06.07.04 Mecasermin ® Treatment of growth failure in primary insulin-like growth factor-1 deficiency
10.01.01 Mefenamic Acid  For period pain only
08.03.02 Megestrol Acetate Megace® Treatment of breast cancer
04.01.01 Melatonin 2 mg & 3 mg capsules 

Use Special Product Ltd

Treatment of insomnia in children and adults with neurological and/or behavioural problems, including ADHD and autism 

Dot Also in older adults with dementia where alternative hypnotics have failed

 See APC documents below

SecondLine-

04.01.01 Melatonin tablets Circadin®

Treatment of insomnia in children and adults with neurological and/or behavioural problems, including ADHD and autism
Dot Also in older adults with dementia where alternative hypnotics have failed

See APC documents below

Preferred-

10.01.01 Meloxicam  For long acting drug for morning stiffness
08.01.01 Melphalan  Treatment of breast and ovarian cancer, multiple myeloma, polycythemia vera, neurorblastoma, malignant melanoma and soft -tissue sarcoma
04.11 Memantine tablets 

Mild to moderate dementia in Alzheimer's disease.

For second line use if intolerant of AChEs or severe dementia

SecondLine-

06.05.01 Menotrophin (human menopausal gonadotrophins)  Treament of male and female infertility

05.04.04 Mepacrine   Treatment of giardiasis
10.01.03 Mepacrine  Treatment of discoid lupus erythematosis
15.02 Mepivacaine 

Infiltration anaesthesia and nerve block in dentistry

15.02 Mepivacaine/adrenaline 

Infiltration anaesthesia and nerve block in dentistry

03.04.02 Mepolizumab  Treatment for severe refractory eosinophilic asthma
09.08.01 Mercaptamine  Treatment of nephropathic cystinosis
09.08.01 Mercaptamine (cysteamine) eye drops   Treatment of cystinosis
01.05.03 Mercaptopurine  Treatment ulcerative colitis,crohns disease and auto immune hepatitis
08.01.03 Mercaptopurine  Treatment of leukemia
05.01.02.02 Meropenem  Treatment of aerobic and anaerobic gram-positive and
gram-negative infections
01.05.01 Mesalazine  Treatment of exacerbations and maintenance of remission of Ulcerative Colitis, maintenance of remission of Crohn's ileo-colitis
08.01 Mesna IV  Prevention or urothelial toxicity
06.01.02.02 Metformin MR tablets  Intolerance to standard release form
06.01.02.02 Metformin standard release tablets 
04.10.03 Methadone 

Opioid dependence

Specialist to provide a share care agreement as required

01.05 Methotrexate  Unresponsive or chronically active Crohn’s disease
13.05.03 Methotrexate 

Treatment of psoriasis

10.01.03 Methotrexate oral & sc injection  Metoject®

Treatment of rheumatoid arthritis - must prescribe by brand

08.01.03 Methotrexate oral, IV, Intrathecal  Treatment of acute lymphoblastic leukaemia, Choriocarcinoma, Non-Hodgkin's lymphoma, Solid tumours, meningeal cancer and lymphoma
09.01.03 Methoxy polyethylene glycol-epoetin beta  Treatment of anaemia in cancer patients receiving chemotherapy

Treatment of renal anaemia: locally, supplies provided by secondary care
Outside area: SC may be required

15.01.02 Methoxyflurane  Emergency relief of moderate to severe pain in conscious patients with trauma and associated pain
13.08.01 Methyl-5-Aminolevulinate  Treatment of superficial or nodular basal cell carcinoma in combination with photodynamic therapy
01.06.06 Methylnaltrexone  Treatment of opioid induced constipation in terminally ill where response to other laxatives is inadequate
04.04 Methylphenidate IR tablets & XL capsules Equasym® XL Medikinet® XL

Treatment of Attention Deficit Hyperactivity Disorder

Preferred-

04.04 Methylphenidate XL tablets Concerta® XL

Treatment of Attention Deficit Hyperactivity Disorder

SecondLine-

04.06 Metoclopramide subcut injection 

Used for nausea and vomiting in palliative care

Refer to APC CG040 guidance

02.02.01 Metolazone  Treatment of fluid overload in patients with heart failure
02.04 Metoprolol  For migraine prophylaxis, adjunct in hyperthyroidism, arrhythmias
07.02.02 Metronidazole gel  Treatment of bacterial vaginosis
05.01.11 Metronidazole infusion  Treatment of anaerobic infections
05.01.11 Metronidazole oral  Treatment of mild and moderate Clostridium difficile, bacterial vaginosis, giardia and trichomoniasis, and in combination treatment of pelvic inflammatory disease. Part of Helicobacter pylori eradication, and with ciprofloxacin for diverticulitis, if allergy to penicillins
06.07.03 Metyrapone  Diagnosti and treatment of Cushing's syndrome, treatment of resistant oedema due to aldosterone secretion
05.02.04 Micafungin Mycamine® Treatment of systemic fungal infections and prophylaxis of candida infections in stem cell transplantation
04.08.02 Midazolam Epistatus®

Treatment of prolonged, acute convulsive seizures

Licensed preparation can be used under the direction of a specialist only, in patients who have shown a delayed response to the preferred choice

 SecondLine-

04.08.02 Midazolam Buccolam®

Treatment of prolonged, acute convulsive seizures

Preferred-

15.01.04.01 Midazolam injection/infusion  Used in sedation and anaesthesia
15.01.04.01 Midazolam subcut injection 10 mg/2ml 

Used in terminal agitation 

02.07 Midodrine  Treatment of severe orthostatic hypotension due to autonomic dysfunction
08.01.05 Midostaurin capsules 

Treatment of myeloid leukaemia

08.02.04 Mifamurtide ® Treatment of osteosarcoma
07.01.02 Mifepristone  Termination of pregnancy
09.08.01 Miglustat  Treatment of type 1 Gaucher's disease and Niemann-Pick type C disease
02.01.02 Milrinone  Treatment of heart failure
07.04.02 Mirabegron  Use as third line: Treatment of overactive bladder if intolerant to antimuscarinics 
04.03.04 Mirtazapine tablets / orodispersible 
08.01.02 Mitomycin  Treatment of breast cancer, bladder and gastrointestinal tumours
08.01.05 Mitotane  Treatment of adrenocortical carcinoma
08.01.02 Mitoxantrone (Mitozantrone)  Treatment of leukaemia, non-Hodgkin's lymphoma, breast cancer and hepatocellular carcinoma
15.01.05 Mivacurium   Neuromuscular blockade during surgery and intubation
04.04 Modafinil  Treatment of daytime sleepiness associated with narcolepsy with or without cataplexy
03.03.02 Montelukast tablets 
04.07.02 Morphine MR (12 hour release) 

For nociceptive pain

Refer to APC CG003 guidance in yellow section below

Prescribe as Zomorph capsules cost effective brand

For patients who cannot swallow the Zomorph®capsules, the contents can be administered directly in semi-solid food (puree, jam, yoghurt)or via gastric or gastrostomy tubes of a diameter of more than 16 F.G with an open distal end or lateral pores. It is sufficient to rinse the tube with 30ml to 50ml of water.”

04.07.02 Morphine standard release   For initiation for opiates and breakthrough analgesia whilst on MR opiates
04.07.02 Morphine subcut injection 

Used for pain control in palliative care

Refer to APC CG040 guidance in yellow section below

05.01.12 Moxifloxacin infusion  Treatment of community acquired pneumonia and complicated skin and skin structure infections
08.02.01 Mycophenolate Mofetil 

Prophylaxis of transplant rejection in renal, liver and heart transplant patients and treatment of vasculitis, glomerulonephritis and lupus

04.06 Nabilone  Treatment of nausea and vomiting induced by cytotoxic chemotherapy
06.07.02 Nafarelin  Use in controlled ovarian stimulation programmes prior to in-vitro fertilisation
06.07.02 Nafarelin  Treatment of endometriosis
01.06.06 Naloxegol  Treatment of opioid-induced constipation
15.01.07 Naloxone  Treatment of opiod overdose
18 Naloxone  Reversal of postoperative respiratory depression
04.10.03 Naltrexone Nalorex® Adjunct to prevent relapse in detoxified formerly opioid-dependent patients(who have remained opioid-free for at least 7-10 days)
10.01.01 Naproxen tablets 
04.07.04.01 Naratriptan tablets 
08.02.04 Natalizumab  Treatment of highly active relapsing remitting multiple sclerosis
11.03.02 Natamycin eye drops with preservative   Treatment of fungal eye infections
02.04 Nebivolol tablets 
08.01.05 Necitumumab  Treatment of lung cancer
08.01.03 Nelarabine  Treatment of lymphoblastic leukaemia and lymphoblastic lymphoma
05.03.01 Nelfinavir  Treatment of HIV infection in combination with other antiretroviral drugs
05.01.04 Neomycin oral  Pre-operative sterilisation of the bowel, treatment of impending hepatic coma
01.06.02 Neostigmine  Treatment of paralytic ileus
02.03.02 Neostigmine  Treatment of paroxysmal supraventricular tachycardia
07.04.01 Neostigmine  Treatment of post-operative urinary retention
10.02.01 Neostigmine injection  Treatment of myasthenia gravis
15.01.06 Neostigmine injection  Reversal of non-depolarising neuromuscular blockade
10.02.01 Neostigmine oral  Treatment of myasthenia gravis
11.08.02 Nepafenac eye drops  Prevention and treatment of postoperative pain and inflammation and reduction of risk of postoperative macular oedema associated with cataract surgery

04.06 Netupitant & Palonosetron 

Prevention of acute and delayed nausea and vomiting associated with moderately and highly emetogenic chemotherapy

05.03.01 Nevirapine  Treatment of HIV infection in combination with other antiretroviral drugs
05.05.03 Niclosamide  Treatment of tapeworm infections
02.06.02 Nifedipine modified release  Intolerance/adverse reaction to amlodipine if B Blocker co-prescribed



Advice:
Prescribe modified release by brand, consult prescriber advisor for most cost effective brands

08.01.05 Nilotinib  Treatment of chronic myeloid leukaemia
02.06.02 Nimodipine  Prevention of ischaemic neurological deficits following aneurysmal subarachnoid haemorrhage
03.11 Nintedanib  Treatment of Idiopathic Pulmonary Fibrosis
08.01.05 Nintedanib  Treatment of lung cancer
09.08.01 Nitisinone  Treatment of hereditary tyrosinaemia type 1
05.01.13 Nitrofurantoin  Treatment of urinary tract infections, avoid if eGFR < 45ml/min/1.73m²
15.01.02 Nitrous oxide  Maintenance of anaesthesia
08.02.04 Nivolumab  Treatment of melanoma, lung and renal cancer
02.11 Nonacog alpha Factor IX fraction  Treatment and prophylaxis of bleeding in patients with haemophilia B
(congenital factor IX deficiency)
02.11 Nonacog gamma  Treatment and prophylaxis of bleeding in patients with haemophilia B
02.07.02 Noradrenaline/norepinephrine  On-going treatment of hypotensive emergencies with escalating noradrenaline dose requirements
14.05.01 Normal immunoglobulin  For replacement therapy and immunomodulation
04.07.03 Nortriptyline  Unlicensed indication amitriptyline & imipramine intolerance
08.02.03 Obinutuzumab  Treatment of leukaemia and lymphoma
11.08.02 Ocriplasmin intravitreal injection 

Treatment of vitreomacular traction

08.03.04.03 Octreotide 

Reduction of vomiting in palliative care

08.03.04.03 Octreotide  For the relief of symptoms associated neuroendocrine tumours and acromegaly and prevention of complications following pancreatic surgery

08.02.03 Ofatumumab  Treatment of chronic lymphocytic leukaemia
11.03.01 Ofloxacin 0.3% eye drops 
05.01.12 Ofloxacin infusion  Treatment of urinary tract, lower respiratory tract, skin and soft tissue infections, septicaemia
05.01.12 Ofloxacin oral  Only for treatment of pelvic inflammatory disease with oral metronidazole if low risk of gonoccocal infection
01.07.03 Oily phenol injection BP  Treatment of haemorrhoids
13.02.01 Ointment e.g. Hydromol®

High paraffin content (high fire risk)

Twice daily application may be sufficient

04.02.01 Olanzapine 

Treatment of acute and chronic psychoses, mania

Preferred-

08.01.05 Olaparib  Treatment of ovarian, fallopian tube or peritoneal cancer
12.01.03 Olive Oil Ear Drops  Removal of ear wax, where prescription is necessary
11.04.02 Olopatadine 1mg/ml eye drops 
01.05.01 Olsalazine  Treatment of mild active ulcerative colitis and maintenance of remission
03.04.02 Omalizumab 

Prophylaxis of allergic asthma and treatment of chronic spontaneous urticaria

05.03.03.02 Ombitasvir-paritaprevir-ritonavir  Treatment of chronic hepatitis C
02.12 Omega-3-Acid Ethyl Esters  Management of hypertriglyceridaemia, reducing the risk of pancreatitis
01.03.05 Omeprazole capsules 
01.03.05 Omeprazole infusion  Alternative for all licensed indications when oral therapy not appropriate
04.06 Ondansetron 

Treatment in pregnancy, longer-term use in chemotherapy patients

04.06 Ondansetron  Moderately or severely emetogenic chemotherapy or moderately emetogenic radiotherapy (Given just prior to treatment)
Chemotherapy-induced nausea & vomiting (Maximum 5 days of therapy)
Prevention of post-operative nausea & vomiting (Inpatient use only)

04.06 Ondansetron injection  In-patient treatment of post-operative nausea & vomiting
04.06 Ondansetron subcut injection 

For nausea and vomiting in palliative care

04.09.01 Opicapone  Treatment of Parkinson's Disease. For use when entacapone inappropriate
A2.02 Oral supplement - compacts e.g.Fortisip Compact®,Altraplen Compact®,Ensure Compact®

Small Volume Ready to Drink 125ml


Before prescribing use "First Line Nutrition Support" for one month unless request by a registered Dietitian or only prescribe if patient is unable to prepare powdered supplement and requires low volume

A2.02 Oral supplement - juices  e.g.Fresubin Jucy®,Ensure Plus Juce Style®,Fortijuce® Ready to Drink Juice Based

Before prescribing use "First Line Nutrition Support" for one month unless request by a registered Dietitian or only prescribe if patient is unable to prepare powdered supplement and unable to tolerate milk

A2.02 Oral supplement - milkshakes e.g. Aymes Complete®,Ensure Plus Milkshake®,Fortisip bottle® Ready to Drink Milkshake

Before prescribing use "First Line Nutrition Support" for one month unless request by a registered Dietitian or only prescribe if patient is unable to prepare powdered supplement

A2.02 Oral supplement - yoghurt style Ensure Plus Yoghurt Style® Ready to Drink Yogurt style

Before prescribing use "First Line Nutrition Support" for one month unless request by a registered Dietitian or only prescribe if patient is unable to prepare powdered supplement

04.09.02 Orphenadrine  Treatment of Parkinson's disease
08.01.05 Osimertinib  Treatment of lung cancer
08.01.05 Oxaliplatin 

Treatment of colon and colorectal cancer

06.04.03 Oxandrolone   Treatment of Turner's syndrome
04.01.02 Oxazepam   Short term use only
04.08.01 Oxcarbazepine  Treatment of epilepsy
11.07 Oxybuprocaine Hydrochloride 0.4% eye drops  For diagnostic use only
07.04.02 Oxybutynin immediate release tablets  2.5 mg and 5 mg tablets only
04.07.02 Oxycodone MR  

Under the advice of palliative care team only

Prescribe as Longtec cost effective brand

04.07.02 Oxycodone standard release  

Under the advice of palliative care team only

Prescribe as Shortec  cost effective brand 

04.07.02 Oxycodone subcut injection  

For pain control in palliative care

Refer to APC CG040 guidance in yellow section below

08.01.05 Paclitaxel  Treatment of breast, ovarian, lung and pancreatic cancer and Karposi's sarcoma



08.01.05 Paclitaxel - Albumin Bound Formulation  Treatment of breast, lung and pancreatic cancer
08.03.04.01 Palbociclib 

Treatment of breast cancer

08.01 Palifermin  Management of oral mucositis
04.02.02 Paliperidone palmitate long acting injection 

Treatment of schizophrenia in patients who have been stabilised on monthly paliperidone long acting injection for at least 12 months, specialist to complete SIDC

An exception to this would be patients already stabilised on the one monthly injection within primary care. Primary care could consider switching to the three monthly depot injection in line with the Drug Position Statement, the SPC and the checklist for assurance

SecondLine-

04.02.02 Paliperidone palmitate long acting injection 

Treatment of schizophrenia, specialist to complete SIDC

SecondLine-

05.03.05 Palivizumab  Prevention of lower respiratory-tract infection caused by respiratory syncytial virus in children
04.06 Palonosetron  Treatment in pregnancy, longer-term use in chemotherapy patients
04.06 Palonosetron  Moderately and severely emetogenic chemotherapy [Given just prior to treatment]

01.09.04 Pancreatin  Treatment of pancreatic exocrine insufficiency
15.01.05 Pancuronium Bromide  Neuromuscular blockade during surgery, intubation and intensive care
08.01.05 Panitumumab  Treatment of colorectal cancer
08.01.05 Panobinostat  Treatment of multiple myeloma
01.03.05 Pantoprazole injection  All licensed indications only if oral administration is not appropriate
01.03.05 Pantoprazole tablets 
04.07.01 Paracetamol & codeine Co-codamol® 30/500

For nociceptive pain refer to APC pain guidance above

Prescribe as Zapain tablets cost effective brand

 

04.07.01 Paracetamol & codeine 30/500 dispersible tablets Co-codamol® 30/500

swallowing difficulties. NB high sodium content

04.07.01 Paracetamol 120 mg/5ml & 250 mg/5ml oral suspension - sugar free   swallowing difficulties
04.07.01 Paracetamol suppositories  Only when tablets and liquid not appropriate - ensure licensed strengths used
04.07.01 Paracetamol tablets 
15.01.04.02 Parecoxib  Treatment of postoperative pain
09.06.04 Paricalcitol Zemplar® Prevention and treatment of secondary hyperparathyroidism
06.05 Pasireotide diaspartate  Treatment of Cushing's disease
06.05 Pasireotide pamoate  Treatment of acromegaly
08.01.05 Pazopanib  Treatment of renal cell carcinoma and soft tissue sarcoma
09.01.06 Pegfilgrastim  Reduction in neutropenia
08.02.04 Peginterferon alfa (2a & 2b)  Treatment of hepatitis B and C
06.05.01 Pegvisomant Somavert® Treatment of acromegaly
08.01.05 Pembrolizumab 

Treatment of metastatic non-small-cell lung cancer & urothelial cancer

08.01.03 Pemetrexed Alimta® Treatment of lung cancer and mesothelioma
09.08.01 Penicillamine  Treatment of Wilson's disease
Specialist to provide a share care agreement as required
09.08.01 Penicillamine  Treatment of Cystinuria – dissolution and prevention of cystine stones in children
10.01.03 Penicillamine  Severe active rheumatoid arthritis
18 Penicillamine  Treatment of lead poisoning
05.04.08 Pentamidine Isetionate  Treatment and prophylaxis of Pneumocystis jirovecii (Pneumocystis carinii) pneumonia
Treatment of cutaneous leishmaniasis and trypanosomiasis
08.01.05 Pentostatin  Treatment of hairy cell leukaemia
04.08.01 Perampanel  Adjunctive treatment of partial onset seizures with or without secondary generalised seizures
04.02.01 Pericyazine 
02.05.05.01 Perindopril erbumine tablets 
13.10.04 Permethrin 5% cream  Treatment of scabies
04.02.01 Perphenazine 
08.03.04.01 Pertuzumab 

Treatment of breast cancer

08.01.05 Pertuzumab with trastuzumab & docetaxel 

Treatment of HER2-postive breast cancer

04.08.01 Phenobarbital  Treatment of epilepsy - MHRA advises prescribing by brand to avoid loss of seizure control by switching brands

05.01.01.01 Phenoxymethylpenicillin  Treatment of pharyngitis/tonsillitis where antibiotics required
11.05 Phenylephrine 2.5% & 10% eye drops  
02.07.02 Phenylephrine injection  Treatment of hypotension
04.08.01 Phenytoin  Treatment of epilepsy - MHRA advises prescribing by brand to avoid loss of seizure control by switching brands
01.06.05 Phosphates  Bowel cleansing preparation (not treatment for constipation)
11.06 Pilocarpine 1% & 2% eye drops 

Treatment of glaucoma

Preferred-

11.06 Pilocarpine 2% eye drops  
11.06 Pilocarpine 4% eye drops  Treatment of glaucoma
13.05.03 Pimecrolimus  Short-term treatment of mild to moderate atopic eczema when topical corticosteroids cannot be used
04.02.01 Pimozide Orap®
06.01.02.03 Pioglitazone tablets 
05.01.01.04 Piperacillin/tazobactam  Treatment of bacterial infections
04.09.03 Piracetam Nootropil® Adjunctive treatment of cortical myoclonus
03.11 Pirfenidone  Treatment of Idiopathic Pulmonary Fibrosis
04.04 Pitolisant  Treatment of narcolepsy with or without cataplexy
05.01.01.05 Pivmecillinam  Treatment of urinary tract infections
see antibiotic guidelines for advice on dose

08.01.02 Pixantrone  Treatment of Non-Hodgkin B-cell Lymphomas
09.01.07 Plerixafor  Treatment of lymphoma and multiple myeloma
11.03.01 Polihexanide 0.02% eye drops   Treatment of protozoal eye infections in combination with one other agent
11.08.01 Polyvinyl alcohol eye drops SnoTears® In use expiry is 28 days
08.01.05 Ponatinib Iclusig

Treatment of chronic myeloid leukaemia & acute lymphoblastic leukaemia

08.01.05 Porfimer Sodium  Photodynamic therapy of lung and oesophageal cancer
05.02 Posaconazole   Treatment of invasive aspergillosis, chromoblastomycosis, fusariosis, mycetoma and coccidioidomycosis
11.08.02 Povidone iodine 5% eye drops  Cutaneous peri-ocular and conjunctival antisepsis prior to ocular surgery
A2.02 Powdered supplements e.g. Aymes Shake®,Complan Shake®,Foodlink Complete® Powdered sachet needs to be made up with full fat milk


Before prescribing use "First Line Nutrition Support" for one month unless request by a registered Dietitian

04.09.01 Pramipexole 

Treatment of Parkinson's disease, prescribe as Pipexus cost effective brand

Preferred-

04.09.04 Pramipexole tablets 

Treatment of Restless Legs Syndrome (RLS) - review patient after 3 months  

02.09 Prasugrel 

Prevention of atherothrombotic events in patients with acute coronary syndrome undergoing percutaneous coronary intervention

SecondLine-

02.12 Pravastatin tablets 
05.05.05 Praziquantel  Treatment of schistosomiasis and tapeworm infections
11.04.01 Prednisolone 0.5% eye drops 
11.04.01 Prednisolone 0.5% eye drops  
06.03.02 Prednisolone 25 mg tablets  Use in haematological disorders and oncology where large doses required
06.03.02 Prednisolone tablets  Prescribe recommended strengths only
04.07.03 Pregabalin   Use as fourth line: Prescribe the most appropriate dose twice daily.
Use if other choices or combinations ineffective or not tolerated

Prescribe generically for all indications

04.08.01 Pregabalin  Treatment of epilepsy
15.02 Prilocaine Hydrochloride  Local anaesthetic for use in infiltration anaesthesia, nerve blocks and spinal anaesthesia
04.08.01 Primidone  Treatment of epilepsy - MHRA advises prescribing by brand to avoid loss of seizure control by switching brands

08.01.05 Procarbazine 
04.02.01 Prochlorperazine 
04.09.02 Procyclidine  Treatment and symptomatic relief of all forms of Parkinson's disease . Control of extrapyramidal symptoms induced by neuroleptic drugs
06.04.01.02 Progesterone pessaries, vaginal gel, injection 

Treatment of infertility

02.03.02 Propafenone  Treatment of arrhythmias
11.03.01 Propamidine 0.1% eye drops  Treatment of protozoal eye infections in combination with one other agent
15.01.01 Propofol  Induction and maintenance of sedation and anaesthesia
02.04 Propranolol  For hyperthyroid patients, patients with anxiety or increased sympathetic drive
04.07.04.02 Propranolol modified realease capsules  Prophylaxis of migraine
11.08.01 Propylene glycol & lipid eye drops Systane Balance® Multi-dose preserved 10ml bottle, in use expiry is 6 months
11.08.01 Propylene glycol eye drops Systane® Multi-dose preserved 10ml bottle, in use expiry is 6 months
11.08.01 Propylene glycol unit dose vials Systane® Preservative free
06.02.02 Propylthiouracil 

Treatment of hyperthyroidism

SecondLine-

02.08.03 Protamine sulphate  Used to counteract the anticoagulant effects of heparin
02.11 Protein C Concentrate Ceprotin® Treatment and prophylaxis of protein C deficiency
11.07 Proxymetacaine Hydrochloride 0.5% eye drops  For diagnostic use only
01.06.07 Prucalopride 

Chronic constipation when other laxatives fail to provide an adequate response

See NICE guidance MTG36 below

05.01.09 Pyrazinamide  Treatment of tuberculosis in combination with other drugs
10.02.01 Pyridostigmine   Treatment of myasthenia gravis
05.01.09 Pyridoxine  

TB prophylaxis for renal transplant patients as per BTS guidelines) (9 months)

05.04.01 Pyrimethamine   Treatment of toxoplasmosis
04.02.01 Quetiapine standard release tablets 

Treatment of schizophrenia and episodes of mania

Preferred-

04.02.01 Quetiapine XL  Biquelle®

Treatment of schizophrenia and episodes of mania

Prescribe by cost effective brand

SecondLine-

06.07.01 Quinagolide ® Treatment of hyperprolactinaemia
01.03.05 Rabeprazole tablets 
06.04.01.01 Raloxifene  

Treatment of postmenopausal women at high risk of breast cancer who have severe osteoporosis

06.04.01.01 Raloxifene Hydrochloride Evista®

Treatment of osteoporotic fragility fractures in postmenopausal women

05.03.01 Raltegravir  HIV infection in combination with other antiretroviral drugs
08.01.03 Raltitrexed  Palliation of colorectal cancer
02.05.05.01 Ramipril capsules/tablets 
08.01.05 Ramucirumab 
11.08.02 Ranibizumab intravitreal injection 

Treatment of neovascular wet age-related macular degeneration (Wet AMD), macular oedema and choroidal neovascularisation

01.03.01 Ranitidine injection  All licensed indications if oral administration is not appropriate
01.03.01 Ranitidine oral solution 75mg/5mL sugar free   Swallowing difficulties/paediatrics
01.03.01 Ranitidine tablets 
02.06.03 Ranolazine  Add-on therapy for the treatment of angina who are inadequately controlled or intolerant to first-line antianginal therapies
04.09.01 Rasagiline 

Treatment of Parkinson's disease

Preferred-

10.01.04 Rasburicase  Prophylaxis and treatment of hyperuricaemia
08.01.05 Regorafenib Stivarga® Treatment colorectal cancer and gastrointestinal stromal tumours

15.01.04.03 Remifentanil  Analgesia and enhancement of anaesthesia and use in intensive care patients
03.04.02 Reslizumab  Treatment of severe eosinophilic asthma
04.08.01 Retigabine  Adjunctive treatment of focal seizures with ot withput secondary generalisation
05.03.05 Ribavirin  Treatment of respiratory syncytial virus
05.03.05 Ribavirin  Treatment of hepatitis C
08.03.04.01 Ribociclib 

Previously untreated hormone receptor-positive HER2-negative, locally advanced or metastatic breast cancer

05.01.09 Rifabutin  Treatment of pulmonary tuberculosis, in combination with other drugs
05.01.09 Rifampicin  Only for prophylaxis of meningococcal meningitis
05.01.09 Rifampicin injection & oral  Treatment of tuberculosis, atypical strains of Mycobacteria, leprosy, brucellosis, legionnaires Disease and serious staphylococcal infections
05.01.07 Rifaximin Targaxan® Treatment of hepatic encephalopathy
05.03.01 Rilpivirine   HIV infection in combination with other antiretroviral drugs
04.09.03 Riluzole Rilutek® To extend life or the time to mechanical ventilation for patients with amyotrophic lateral sclerosis - motor neurone disease
02.05.01 Riociguat Adempas® Treatment of pulmonary arterial hypertension and thromboembolic pulmonary hypertension
06.06.02 Risedronate tablets (weekly)  Intolerance to alendronate
04.02.02 Risperidone long acting injection 

Treatment of schizophrenia and other psychoses

SecondLine-

04.02.01 Risperidone tablets 

Treatment of acute and chronic psychoses, mania 

Preferred-

05.03.01 Ritonavir  HIV infection in combination with other antiretroviral drugs
08.02.03 Rituximab  Treatment of lymphomas and chronic lymphocytic leukaemia, and anti-neutrophil cytoplasmic antibody-associated vasculitis


09.01.04 Rituximab 

Treatment of idiopathic thrombocytopenic purpura and warm autoimmune haemolytic anaemia

10.01.03 Rituximab  

Treatment of rheumatoid arthritis - patients with contraindication to anti-TNF therapy and rheumatoid arthritis - patients unable to take Methotrexate

02.08.02 Rivaroxaban  Prophylaxis of venous thromboembolism following knee or hip surgery -
full course to be given post operation by provider
02.08.02 Rivaroxaban 

Treatment and prevention of thromboembolic events, and stroke prevention in atrial fibrillation

Specialist to complete SIDC

04.11 Rivastigmine   Treatment of Dementia associated with Parkinson’s disease
04.11 Rivastigmine capsules 

Mild to moderate dementia in Alzheimer's disease

Preferred-

15.01.05 Rocuronium   Neuromuscular blockade during surgery, intubation and intensive care
09.01.04 Romiplostim 

Treatment of idiopathic thrombocytopenic purpura

04.09.01 Ropinirole MR 

Treatment of Parkinson's disease, prescribe as Spiroco cost effective brand

Preferred-

04.09.04 Ropinirole tablets 

Treatment of Restless Legs Syndrome (RLS) -- review patient after 3 months  

15.02 Ropivacaine   Used in anaesthesia and pain management
02.12 Rosuvastatin tablets  For use in exceptional circumstances such as HIV co-mobidity and adverse reaction to preferred choices
04.09.01 Rotigotine patch 

Treatment of Parkinson's disease

Preferred-

04.09.04 Rotigotine patch 

Treatment of Restless Legs Syndrome (RLS) - review patient after 3 months  

04.08.01 Rufinamide Inovelon® Lennox-Gestaut Syndrome
08.01.05 Ruxolitinib  Treatment of myelofibrosis
02.05.05 Sacubitril & valsartan 

Treatment of symptomatic chronic heart failure with reduced ejection fraction.

Specialist to complete SIDC

04.09.01 Safinamide  Treatment of Parkinson's disease
03.01.01.01 Salbutamol 100mcg/dose easyhaler 
03.01.01.01 Salbutamol 100mcg/dose metered dose inhaler 
03.01.01.01 Salbutamol Easi-breathe Salamol®
07.01.03 Salbutamol infusion  Management of premature labour
03.01.01.01 Salmeterol 50mcg accuhaler 
03.01.01.01 Salmeterol metered dose inhaler 
09.04.01 Sapropterin Dihydrochloride   Treatment of phenylketonuria and tetrahydrobiopterin deficiency
05.03.01 Saquinavir  HIV infection in combination with other antiretroviral drugs
10.01.03 Sarilumab 
09.08.01 Sebelipase alfa  Replacement therapy in lysosomal acid lipase deficiency
13.05.03 Secukinumab 

Treatment plaque psoriasis, psoriatic arthritis and ankylosing spondylitis

04.09.01 Selegiline Hydrochloride 

Treatment of Parkinson’s disease and symptomatic Parkinsonism

Preferred-

09.05.05 Selenium Selenase® Prevention of selenium deficiency in patients receiving parenteral nutrition, treatment of proven selenium deficiency that cannot be cured by nutrition alone
02.05.01 Selexipag  Treatment of pulmonary arterial hypertension
04.03.03 Sertraline tablets 

Treatment of anxiety, depression, obsessive compulsive disorder and post traumatic stress in children if fluoxetine is unsuccessful or not tolerated

SecondLine-

04.03.03 Sertraline tablets 
09.05.02.02 Sevelamer  Treatment of hyperphosphataemia in patients with haemodialysis
15.01.02 Sevoflurane  Induction and maintenance of general anaesthesia
02.05.01 Sildenafil  Pulmonary arterial hypertension
07.04.05 Sildenafil tablets 
11.08.01 Silicone eye drops Opsil® Standard or thick viscosity for artificial eyes
05.03.03.02 Simeprevir 

Treatment of genotype 1 & 4 chronic hepatitis C

02.12 Simvastatin tablets 
08.02.02 Sirolimus 

Suppression of renal transplant rejection

06.01.02.03 Sitagliptin tablets 
10.01.03 Sodium Aurothomalate (Gold) Myocrisin®

Active progressive rheumatoid arthritis, juvenile idiopathic arthritis

09.08.01 Sodium Benzoate   Treatment of hyperammonaemia due to urea cycle disorders and non-ketotic hyperglycinaemia
12.01.03 Sodium Bicarbonate ear drops  Removal of ear wax, where prescription is necessary
03.07 Sodium chloride (Hypertonic)  Nebulised to mobilise lower respiratory tract secretion in mucous consolidation
11.08.01 Sodium Chloride 5% eye drops ODM 5® Preservative free, in use expiry is 90 days
11.08.01 Sodium Chloride 5% eye ointment  
11.08.02 Sodium chondroitin & sodium hyaluronate prefilled syringe Viscoat® For peri-operative use
11.99.99.99 Sodium citrate eye drops  Treatment of corneal acid and alkali burns
06.06.02 Sodium clodronate oral  Treatment of osteolytic lesions, hypercalcaemia and bone pain assosiated with skeletal metastases in patients with breast cancer or multiple myeloma
11.04.02 Sodium Cromoglicate 2% eye drops 
11.04.02 Sodium Cromoglicate 2% eye drops  
09.08.01 Sodium Dichloroacetate  Treatment of pyruvate dehydrogenase defects
10.01 Sodium hyaluronate  Treatment of pain in osteoarthritis of the knee
Not recommended by NICE
11.08.01 Sodium Hyaluronate & dexpanthanol eye drops Hylo-Care® Multi-dose preservative free 10ml bottle, in use expiry is 6 months
11.08.01 Sodium hyaluronate & trehalose eye drops Thealoz Duo® Multi-dose 10ml preservative free bottle, in use expiry is 90 days
Preservative free unit dose vials
11.04.02 Sodium Hyaluronate 0.05% & Ectoin 2% eye drops  Hylo-Dual® To be used only when an antihistamine and lubricant both required

In use expiry is 6 months

11.08.01 Sodium Hyaluronate 0.2% eye drops  Blink Intensive Tears® Multi-dose 10ml preserved bottle, in use expiry is 45 days
Unit dose vials is preservative free
11.08.01 Sodium Hyaluronate 0.2% eye drops  Hydramed® Multi-dose 10ml preservative free bottle, in use expiry is 90 days
11.08.01 Sodium Hyaluronate 0.3% gel Vismed Gel® Preservative free products: multi-dose 10ml bottle in use expiry is 90 days. Also includes unit dose vials

Use only if intolerant to paraffin base preparation

11.08.01 Sodium Hyaluronate 0.4% eye drops  Clinitas Multi® Multi-dose preservative free 10ml bottle, in use expiry is 90 days
11.08.01 Sodium Hyaluronate 0.4% unit dose vials  Clinitas® Preservative free
11.08.02 Sodium hyaluronate prefiled syringe Provisc® for peri-operative use
18 Sodium nitrite/sodium thiosulfate  Treatment of acute life-threatening cyanide poisoning
09.08.01 Sodium Phenybutyrate  Adjunct in long-term treatment of urea cycle disorders. It is indicated as adjuvant in all patient with neonatal onset disease and in those with late onset disease who have a history of hyperammonaemic encephalopathy
01.06.05 Sodium picosulfate/magnesium sulphate  Bowel cleansing preparation not treatment for constipation
05.04.05 Sodium Stibogluconate  Treatment of Leishmaniasis
04.08.01 Sodium Valproate 

Treatment of epilepsy in males

04.08.01 Sodium Valproate 

Treatment of epilepsy in females of child-bearing potential

SecondLine-

01.06.05 Sodium, magnesium & potassium sulfates  Bowel cleansing preparation not treatment for constipation
05.03.03.02 Sofosbuvir 

Treatment of hepatitis C

05.03.03.02 Sofosbuvir-velpatasvir 

Treatment of hepatitis C

05.03.03.02 Sofosbuvir-velpatasvir-voxilaprevir Vosevi®

Treatment of chronic hepatitis C

07.04.02 Solifenacin 5 mg tablets  Use as third line: only after at least 2 other antimuscarinic drugs have been tried
06.05.01 Somatropin 

Deficiency of growth hormone

02.04 Sotalol  Treatment of cardiac arrhythmias
A2.05.02 Starch based thickener Resource ThickenUp®

Thickeners in sachet form should not be used and converted to tins

13.11.07 Sterile Larvae (Maggots)  Debridement of sloughing wounds

The secondary care clinician is classified as the ‘specialist’ for secondary care led patients receiving sterile larvae therapy in the community via community nursing services and would assume responsibility for supply of larvae

02.10.02 Streptokinase  Treatment of acute myocardial infarction, deep vein thrombosis, pulmonary embolism, acute arterial thromboembolism and central retinal thrombosis
05.01.09 Streptomycin   Treatment of tuberculosis, in combination with other drugs
15.01.06 Sugammadex  Reversal of neuromuscular blockade induced by rocuronium or vecuronium
01.05.01 Sulfasalazine  Induction and maintenance of remission of ulcerative colitis; treatment of active Crohn's Disease
10.01.03 Sulfasalazine 

Treatment of active rheumatoid arthritis

04.02.01 Sulpiride 
04.07.04.01 Sumatriptan tablets 
08.01.05 Sunitinib  Treatment of gastro-intestinal and pancreatic tumours and renal cell carcinoma
02.11 Susocotog alfa  Treatment of bleeding episodes in patients with acquired haemophilia caused by antibodies to Factor VIII
15.01.05 Suxamethonium Chloride  Neuromuscular blockade during surgery and intubation
08.02.02 Tacrolimus 

Prophylaxis of organ rejection – Renal, liver and heart transplant
Prescribe by brand

13.05.03 Tacrolimus  Short term treatment of moderate to severe atopic eczema either unresponsive to, or in patients intolerant of conventional therapy.
02.05.01 Tadalafil  Treatment of pulmonary arterial hypertension
07.04.05 Tadalafil 10 mg & 20 mg (PRN formulation)  HIV patients only
08.01.05 Talimogene laherparepvec  Treatment of melanoma
06.05.01 Tamoxifen  Treatment of anovulatory infertility
08.03.04.01 Tamoxifen  Treatment of breast cancer
07.04.01 Tamsulosin modified release capsules 

Prescribe as Pamsvax cost effective brand

04.07.02 Tapentadol Palexia SR®

Treatment of pain that can only be treated with opioids in line with pain guidelines.

Specialist to complete Specialist Drug Checklist on initiation before GP can continue prescribing

SecondLine-

05.01.07 Tedizolid  Treatment of acute bacterial skin and skin structure infections
08.01.03 Tegafur/gimeracil/oteracil  Treatment of gastric cancer
05.01.07 Teicoplanin  Treatment and prophylaxis of bacterial infections in line with local antibiotic guidelines
05.03.03.02 Telaprevir Incivo®
05.03.03.01 Telbivudine  Treatment of chronic hepatitis B
04.01.01 Temazepam tablets 
05.01.01.02 Temocillin  Treatment of bacterial infections in line with local antibiotic guidelines
08.01.05 Temoporfin  Photodynamic therapy of head and neck cancer
08.01.05 Temozolomide  Treatment of glioblastoma multiforme and malignant glioma
08.01.05 Temsirolimus  Treatment of renal cell carcinoma and mantle cell lymphoma
02.10.02 Tenecteplase  Treatment of acute myocardial infarction
05.03.01 Tenofovir   Hepatitis B and HIV infection in combination with other antiretroviral drugs
05.03.01 Tenofovir/cobicistat/elvitegravir/emtricitabine 
05.03.01 Tenofovir/efavirenz/emtricitabine   Treatment of HIV infection
05.03.01 Tenofovir/emtricitabine  Treatment of HIV infection
05.03.01 Tenofovir/emtricitabine/rilpivirine  Treatment of HIV infection
07.04.01 Terazosin tablets 
03.01.01.01 Terbutaline 500mcg/dose turbohaler 
07.01.03 Terbutaline infusion  Management of uncomplicated premature labour
08.02.04 Teriflunomide  Treatment of relapsing remitting multiple sclerosis
06.06.01 Teriparatide 

Treatment of postmenopausal osteoporosis

06.05.02 Terlipressin  Treatment of bleeding oesophageal varices
06.04.02 Testosterone   Androgen deficiency and male hypogonadism, induction/augmentation of male puberty
04.09.03 Tetrabenazine  Treatment of movement disorders due to Huntingdon's chorea, hemiballismus, senile chorea and related neurological conditions and severe tardive dyskinesia
11.07 Tetracaine Hydrochloride 1% eye drops 
05.01.10 Thalidomide  Treatment of myeloma and treatment of Bechet's Syndrome (unlicensed indication)
03.01.03 Theophylline modified release   Must be prescribed by BRAND
17.01 TheraBite jaw rehabilitation device pads & accessories 

Treatment of trismus

15.01.01 Thiopental sodium  Used in general anaesthesia, reduction of intracranial pressure, and in status epilepticus if all other measures have failed
08.01.01 Thiotepa  Treatment of solid tumours, malignant effusions and conditioning treatment prior to haematopoetic stem cell transplantion
05.05.07 Tiabendazole  Tocilizumab for the treatment of rheumatoid arthritis
04.08.01 Tiagabine Gabitril® Adjunctive treatment for local seizures with or without secondary generalisation that are not satisfactorily controlled by other antiepileptics
02.09 Ticagrelor Brilique®

Prevention of atherothrombotic events in patients with Acute Coronary Syndrome - Use in combination with aspirin for 12 months only

SecondLine-

05.01.01.04 Ticarcillin with clavulanic acid  Treatment of infections due to Pseudomonas and Proteus spp
05.01.03 Tigecycline  Treatment of complicated skin, soft-tissue and complicated abdominal infections caused by multiple-antibacterial resistant organisms
11.06 Timolol 0.1% eye drops Tiopex®

Once daily

SecondLine-

11.06 Timolol 0.25% eye drops 

Treatment of glaucoma

Preferred-

11.06 Timolol 0.25% eye drops  

Treatment of glaucoma

SecondLine-

02.08.01 Tinzaparin  Prophylaxis and treatment of thrombosis and embolism in pregnancy - see links below
02.08.01 Tinzaparin  In most scenarios (e.g. DVT prophylaxis in surgical settings)
LMWHs are within tariff and therefore acute provider should supply
02.08.01 Tinzaparin  Surgical prophylaxis
08.01.03 Tioguanine  Treatment of leukemias
03.01.02 Tiotropium Spiriva®Respimat®
03.01.04 Tiotropium & olodaterol Spiolto Respimat®
03.01.02 Tiotropium 2.5mcg  Spiriva Respimat®

Add-on maintenance treatment for asthma

Preferred-

03.01.02 Tiotropium handihaler Spiriva®, Braltus®
05.03.01 Tipranavir Aptivus HIV infection in combination with other antiretroviral drugs
02.09 Tirofiban  Treatment of myocardial infarction
08.01.05 Tivozanib Fotivda

Treatment of advanced renal cell carcinoma

10.02.02 Tizanidine  Spasticity associated with multiple sclerosis or spinal cord injury or disease
05.01.04 Tobramycin  Treatment of bacterial infections caused by susceptible micro-organsisms
05.01.04 Tobramycin nebuliser solution  Treatment of chronic pulmonary Pseudomonas aeruginosa infection in cystic fibrosis.
Exisiting patients until repatiated to secondary care
05.01.04 Tobramycin nebuliser solution  Treatment of chronic pulmonary Pseudomonas aeruginosa infection in cystic fibrosis
10.01.03 Tocilizumab oral & sc injection 

Treatment of rheumatoid arthritis, juvenile idiopathic arthritis (Adults) and giant cell arteritis

 

10.01 Tofacitinib 

Treatment of rheumatoid arthritis

04.09.01 Tolcapone 

Treatment of Parkinson's Disease. For use when entacapone inappropriate

SecondLine-

07.04.02 Tolterodine IR tablets 
07.04.02 Tolterodine XL tablets Neditol XL® For oxybutynin intolerance. Prescribe Neditol XL brand
06.05.02 Tolvaptan Samsca® Treatment of hyponatraemia secondary to syndrome of inappropriate antidiuretic hormone secretion
06.05.02 Tolvaptan Jinarc®

To slow the progression of cyst development and renal insufficiency of autosomal dominant polycystic kidney disease

A5.06.01 Topical negative pressure therapy  Treatment of acute, chronic and surgical wounds

The secondary care clinician is classified as the ‘specialist’ for secondary care led patients receiving topical negative pressure therapy in the community via community nursing services and would assume responsibility for supply of consumables

04.07.04.02 Topiramate  Prophylaxis of migraine
04.08.01 Topiramate  Treatment of epilepsy including Lennox-Gestaut Syndrome
08.01.05 Topotecan  Treatment of ovarian, cervical and lung cancer
08.03.04.01 Toremifene  Treatment of breast cancer
08.01.05 Trabectedin  Treatment of soft tissue sarcoma and ovarian cancer
04.07.02 Tramadol 50 mg standard release capsules 

All licensed indications - further information refer to APC CG003 guidance in yellow section below

04.07.02 Tramadol 50 mg standard release capsules 

All licensed indications  - further information refer to APC CG003 guidance in yellow section below

04.07.02 Tramadol MR 

Use only for longer duration required for overnight pain

Prescribe as Marol or Zytram tablets most cost effective brand, if capsules are required use Maxitram capsules

For neuropathic pain further information refer to APC CG003 guidance in yellow section below 

08.01.05 Trametinib  Treatment of melanoma
02.11 Tranexamic Acid  Prevention and treatment of haemorrhages due to general or local fibrinolysis
08.01.05 Trastuzumab emtansine  Treatment of breast, oesophageal and stomach cancer
11.06 Travoprost 40 micrograms/ml eye drops  

Treatment of glaucoma

SecondLine-

11.06 Travoprost 40 micrograms/ml with Timolol 0.5% eye drops 

Treatment of glaucoma

SecondLine-

04.03.01 Trazodone 
08.01.01 Treosulfan 

Treatment of ovarian cancer

08.01.05 Tretinoin  Induction of remission in acute promyelocytic leukaemia
09.08.01 Trientine dihydrochloride  Treatment of Wilson’s disease
04.02.01 Trifluoperazine 
11.03.03 Trifluorothymidine eye drops (Trifluridine)  Treatment of ophthalmic viral infections
08.01.03 Trifluridine/tipiracil  Treatment of colorectal cancer
04.09.02 Trihexyphenidyl  Treatment of all forms of Parkinsonism
05.01.08 Trimethoprim oral  Use as third line: for treatment of urinary tract infections
06.07.02 Triptorelin  Treatment of central precocious puberty
06.07.02 Triptorelin  Treatment of endometriosis
08.03.04.02 Triptorelin  Treatment of prostate cancer
11.05 Tropicamide 0.5% & 1% eye drops   For diagnostic use only
11.05 Tropicamide 1% eye drops   For diagnostic use only
11.08.02 Tropicamide/phenylephrine/lidocaine   For mydriasis and intraocular anaesthesia during cataract surgery
07.04.02 Trospium  Treatment of urinary frequency
02.11 Turoctocog alfa  Treatment and prophylaxis of bleeding in haemophilia A
09.08.01 Ubidecarenone (Ubiquinone, Co-enzyme Q10)   Treatment of mitochondrial disorders in children
03.01.02 Umeclidinium Incruse Ellipta®
03.01.04 Umeclidinium & vilanterol Anoro Ellipta®
13.02.01 Urea emollient - urea 5% & glycerin 5%  e.g. Imuderm®

Non-paraffin products

06.05.01 Urofollitropin  Infertility
02.10.02 Urokinase  Lysis of blood clots in thrombosed intravascular catheters and cannulae, extensive acute proximal deep vein thrombosis, acute massive pulmonary embolism, acute occlusive peripheral arterial disease with limb threatening ischemia
01.09.01 Ursodeoxycholic acid  Treatment of primary biliary cirrhosis
01.05.03 Ustekinumab 

Treatment of adult patients with moderately to severely active Crohn's disease

13.05.03 Ustekinumab 

Treatment of plaque psoriasis and psoriatic arthritis

05.03.02.02 Valganciclovir  Treatment and preventions of cytomegalovirus infection
04.02.03 Valproic Acid 

Treatment of manic episodes associated with bipolar disorder in males

 

04.02.03 Valproic Acid 

Treatment of manic episodes associated with bipolar disorder in females of child-bearing potential

SecondLine-

02.05.05.02 Valsartan capsules  Post MI with LVF or LVSD as adjunct
05.01.07 Vancomycin  

Treatment of staphyloccal enterocolitis and pseudomembranous colitis due to Clostridium difficile

Preferred-

05.01.07 Vancomycin for infusion  Treatment of bacterial infections in line wth local antibiotic guidelines
08.01.05 Vandetanib Caprelsa Treatment of thyroid cancer
04.10.02 Varenicline Champix®
06.05.02 Vasopressin  Treatment of pituitary diabetes insipidus and bleeding from oesophageal varices
15.01.05 Vecuronium Bromide  Neuromuscular blockade during surgery and intubation
01.05.03 Vedolizumab 

Treatment of ulcerative colitis and Crohn's disease

09.08.01 Velaglucerase alfa  Treatment of Gaucher’s disease type 1 in children
08.01.05 Vemurafenib  Treatment of melanoma
08.01.05 Venetoclax  Treatment of chronic lymphocytic leukaemia
04.03.04 Venlafaxine modified release capsules  

Known compliance problem or unacceptable side effects with standard release versions

Prescribe generically as capsules excluding Venlafaxine 225 mg capsules which should be prescribed as Vencarm XL

04.03.04 Venlafaxine standard release tablets 

 High doses of above 300 mg should be initiated by a specialist as SI

02.06.02 Verapamil injection  Treatment of cardiac arrhythmias
02.06.02 Verapamil tablets  Also used insupraventricular arrhythmias
11.08.02 Verteporfin  Treatment of exudative (wet) age-related macular degeneration and subfoveal choroidal neovascularisation
04.08.01 Vigabatrin Sabril®

Treatment of epilepsy

08.01.04 Vinblastine Sulphate  Treatment of leukaemias, lymphomas, and some solid tumours
08.01.04 Vincristine  Treatment of leukaemias, lymphomas, solid tumours and multiple myeloma
08.01.04 Vindesine   Treatment of leukaemias, lymphomas and solid tumours
08.01.04 Vinorelbine  Treatment of lung and breast cancer

05.02 Voriconazole  Treatment of fungal infections
11.03.02 Voriconazole 1% with preservative  Treatment of fungal eye infections
04.03.04 Vortioxetine  Treatment of major depressive episodes (to use after 2 other antidepressants drugs have failed)
03.04.02 Wasp Allergen Extracts  Diagnosis and treatment of IgE-mediated allergy to wasp venom
05.03.01 Zidovudine  HIV infection in combination with other antiretroviral drugs; prevention of maternal fetal HIV transmission
05.03.01 Zidovudine/lamivudine  HIV infection in combination with other antiretroviral drugs
09.08.01 Zinc Acetate  Treatment of portal hypertension in children
06.06.02 Zoledronic Acid  Reduction in bone damage in bone malignancies, treatment of osteoporosis, Paget's disease and hypercalcaemia of malignancy
04.07.04.01 Zolmitriptan orodispersible tablets  Swallowing difficulties
04.07.04.01 Zolmitriptan tablets 
04.01.01 Zolpidem tablets 
04.08.01 Zonisamide Zonegran®

Adjunctive therapy for refractory partial seizures with or without secondary generalisation

04.01.01 Zopiclone tablets 
04.02.01 Zuclopenthixol 
04.02.02 Zuclopenthixol decanoate 

Treatment of schizophrenia and other psychoses, particularly with aggression and agitation

Preferred-

Coventry and Warwickshire Area Prescribing Committee