netFormulary Coventry and Warwickshire Area Prescribing Committee NHS
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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
08.03.04.02  Expand sub section  Prostate cancer and gonadorelin analogues
Atrasentan
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Formulary
Red SO
Treatment of prostate cancer
 
   
08.03.04.02  Expand sub section  Gonadorelin analogues
Degarelix (Firmagon®)
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Formulary
Green SI
Treatment of advanced hormone-dependent prostate cancer
 
   
08.03.04.02  Expand sub section  Anti-androgens
Abiraterone
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Formulary
Red SO
Treatment of metastatic castration resistant prostate cancer in asymptomatic or mildly symptomatic men after failure of androgen deprivation therapy in whom chemotherapy is not yet clinically indicated, or when disease has progressed on or after a docetaxel-based chemotherapy regimen 
Link  NICE TA259: Abiraterone for castration resistant prostate cancer
Link  NICE TA387: Abiraterone for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
   
Bicalutamide
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Formulary
Amber SC
Treatment of advanced prostate cancer 
Link  Bicalutamide - shared care agreement
   
Enzalutamide
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Formulary
Red SO
Treatment of prostate cancer
 
Link  NICE TA316: Enzalutamide for metastatic hormone‑relapsed prostate cancer previously treated with a docetaxel‑containing regimen
Link  NICE TA377: Enzalutamide for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
   
Buserelin
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Formulary
Green SA
Treatment of prostate cancer
 
   
Cyproterone
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Formulary
Green SA
Treatment of prostate cancer
 
   
Goserelin
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Formulary
Green SA
Treatment of prostate cancer
 
   
Leuprorelin
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Formulary
Green SA
Treatment of prostate cancer
 
   
Triptorelin
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Formulary
Green SA
Treatment of prostate cancer
 
   
 ....
 Non Formulary Items
Flutamide

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Non Formulary
Non Formulary

Advanced prostate cancer - drug is no longer used routinely

 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Blueteq
High Cost Drug Approval System

Traffic Light Status Information

Status Description

Preferred

Clinicians are free to prescribe these drugs. They are regarded as cost effective choices which have evidence to support their use.  

Second Line

These drugs should only be prescribed in the scenarios described in the formulary after preferred drug(s) have been ruled out.  

Non Formulary

Non-formulary choice - the vast majority of a patient’s needs should be met by use of formulary preferred choices and second line options when appropriate. Therefore the Clinician should only use a non-formularly drug if this can be justified and it is recommended that all such instances are recorded in the patient record.  

Green SA

Specialist Advised – Specialists may simply advise a patient’s GP to initiate these drugs themselves after they have made an initial assessment. Note: SA drugs can be initiated by the specialist according to patient need and also depending on local commissioning arrangements which may mandate, through the contract between provider and commissioner, that all SA drugs are treated as SI.  

Green SI

Specialist Initiation - These drugs must be initiated, i.e. the first dose prescribed, by the specialist and then may be continued when appropriate by the patient’s GP following communication from the specialist.  

Amber SC

Shared Care - Responsibility for prescribing may be transferred from secondary to primary care with the agreement of an individual GP and when agreed shared care arrangements have been established. The specialist MUST stabilize the patient before asking for care to be transferred. Only specialists should initiate these drugs. Prescribing should be transferred to GPs according to an Shared Care Agreement [SCA]   

Red SO

Specialist Only - These drugs are deemed to be not appropriate for prescribing by GPs. Specialists should not ask GPs to prescribe these drugs.   

Black BL

Black Listed Medicines - These drugs are considered inappropriate for prescribing in Coventry & Warwickshire as they are either not cost-effective or of proven benefit or both.   

Not Recommended

Not Recommended - These are specialist drugs that are not recommended for use.  

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