netFormulary Coventry and Warwickshire Area Prescribing Committee NHS
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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
08.01.02  Expand sub section  Anthracyclines and other cytotoxic antibiotics
Cytotoxic Drug Bleomycin
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Formulary
Red SO
Treatment of metastatic germ cell cancer, non-Hodgkins lymphoma and squamous cell carcinoma
 
   
Cytotoxic Drug Dactinomycin
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Formulary
Red SO
Treatment of cancers, principally paediatric
 
   
Cytotoxic Drug Daunorubicin
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Formulary
Red SO
Treatment of leukaemia and AIDs related Kaposi's sarcoma (liposomal formulation only)
 
   
Cytotoxic Drug Doxorubicin
(products not interchangeable)
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Formulary
Red SO
Treatment of leukemia's, lymphomas, ovarian and breast cancer, Karposi's sarcoma and also, of bladder cancers by bladder instillation
 
Link  NICE TA389:Topotecan, pegylated liposomal doxorubicin hydrochloride, paclitaxel, trabectedin and gemcitabine for treating recurrent ovarian cancer
Link  NICE TA465: Olaratumab in combination with doxorubicin for treating advanced soft tissue sarcoma
   
Cytotoxic Drug Epirubicin
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Formulary
Red SO
Treatment of breast cancer and treatment and prophylaxis of superficial bladder cancer
 
   
Cytotoxic Drug Idarubicin
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Formulary
Red SO
Treatment of leukaemias and breast cancer
 
   
Cytotoxic Drug Mitomycin
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Formulary
Red SO
Treatment of breast cancer, bladder and gastrointestinal tumours
 
   
Cytotoxic Drug Mitoxantrone (Mitozantrone)
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Formulary
Red SO
Treatment of leukaemia, non-Hodgkin's lymphoma, breast cancer and hepatocellular carcinoma
 
   
Cytotoxic Drug Pixantrone
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Formulary
Red SO
Treatment of Non-Hodgkin B-cell Lymphomas
 
Link  NICE TA306: Pixantrone monotherapy for treating multiply relapsed or refractory aggressive non-Hodgkin's B‑cell lymphoma
   
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Blueteq
High Cost Drug Approval System

Traffic Light Status Information

Status Description

Preferred

Clinicians are free to prescribe these drugs. They are regarded as cost effective choices which have evidence to support their use.  

Second Line

These drugs should only be prescribed in the scenarios described in the formulary after preferred drug(s) have been ruled out.  

Non Formulary

Non-formulary choice - the vast majority of a patientís needs should be met by use of formulary preferred choices and second line options when appropriate. Therefore the Clinician should only use a non-formularly drug if this can be justified and it is recommended that all such instances are recorded in the patient record.  

Green SA

Specialist Advised Ė Specialists may simply advise a patientís GP to initiate these drugs themselves after they have made an initial assessment. Note: SA drugs can be initiated by the specialist according to patient need and also depending on local commissioning arrangements which may mandate, through the contract between provider and commissioner, that all SA drugs are treated as SI.  

Green SI

Specialist Initiation - These drugs must be initiated, i.e. the first dose prescribed, by the specialist and then may be continued when appropriate by the patientís GP following communication from the specialist.  

Amber SC

Shared Care - Responsibility for prescribing may be transferred from secondary to primary care with the agreement of an individual GP and when agreed shared care arrangements have been established. The specialist MUST stabilize the patient before asking for care to be transferred. Only specialists should initiate these drugs. Prescribing should be transferred to GPs according to an Shared Care Agreement [SCA]   

Red SO

Specialist Only - These drugs are deemed to be not appropriate for prescribing by GPs. Specialists should not ask GPs to prescribe these drugs.   

Black BL

Black Listed Medicines - These drugs are considered inappropriate for prescribing in Coventry & Warwickshire as they are either not cost-effective or of proven benefit or both.   

Not Recommended

Not Recommended - These are specialist drugs that are not recommended for use.  

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